Hi Cait, For what it is worth, while using suppositories, both my 2nd and 3rd RE liked to see numbers over 20, preferably over 25. They both put me on the PIO shots immediately when the suppositories didn't put me over the mark. They may be really intimidating, but you get used to them. And, with the IVF, you are an old pro with the shots. Also, that is a great starting beta!! Can't wait to hear about the doubling number tomorrow!!