mom0810- you do realize 5HTP is an amino acid, right? . . it's a form of tryptophan, which is in tons of foods- such as Turkey, chocolate, and much more.  That's the reason there aren't studies.  I'm certain there are studies in Germany- they've compared it to the most common drugs on the market.  I wish I could read German- because in America only drugs are studied, because there's money behind them.  Nutrition and natural remedies are very poorly studied here, because...