Dr. Sears and HIB vac - Page 2

[carriebft]

http://jama.ama-assn.org/cgi/content...e2=tf_ipsecsha

RESULTS--The age-specific incidence of Hib disease among children less than 5 years old decreased by 71% from 37 per 100,000 persons in 1989 to 11 per 100,000 persons in 1991 (active surveillance data). Haemophilus influenzae meningitis incidence decreased by 82% between 1985 and 1991 (NBMRS data).

CONCLUSION--Our data suggest that conjugate vaccines have already had a marked impact on the incidence of Hib disease in the United States, preventing an estimated 10,000 to 16,000 cases of Hib disease in 1991. The decline of disease in infants less than 1 year old before licensure for this age group warrants further investigation.

more here:

http://pediatrics.aappublications.or...full/110/4/653

mixed bag, IMO.

[alegna]

The real problem is that Hib was not reportable before the vax came out. So they're guesstimating numbers at best.

-Angela

[carriebft]

Second link I put above has lots of info:

http://pediatrics.aappublications.or...l/110/4/653/T1

[carriebft]

There are a couple prevaccination era studies in the AAP reference section which give some clues to actual numbers, but they are isolated to certain cities and areas.