detox pathway guinea pig - Page 28

[Theloose]

Originally Posted by neveryoumindthere

for me it was pretty clear b/c i was not doing anything at all (ie, supps) at the time
my ND mentioned, iron is one of the ffirst things you have trouble absorbing when you are gluten intolerant/celiac

Yeah. Mine went from about an 8 while pregnant to about a 12 or 13 when dd was 9mo. no supplements, but I wasn't menstruating and I cut out gluten dairy and soy all at once. It was a major lead for me to really take the gluten stuff seriously though!

[neveryoumindthere]

mine went from deficient pre-preg to 112 while pregnant

[Theloose]

Originally Posted by neveryoumindthere

mine went from deficient pre-preg to 112 while pregnant

iron can go that high!? I must be thinking of a different test!

[neveryoumindthere]

hm, don't quote me on that. I'm in Canada, maybe they use diff. ranges??? or maybe I'm getting confused btwn iron, ferritin, and/or something else.

I love how we're chatting on 2 diff. threads at the same time.

[coolgirl]

Originally Posted by whoMe

Okay, next update.

I started taking a little taurine myself - 500mg for about 2-3 days. Some people do 3g+, so this really seems like a small amount. I'm hoping it will help regulate calcium ion channels and glutamate levels, increasing sulfate available for other purposes like making my joints less crackly.

No obvious effect.

BUT my knee is horribly bruised, right over the kneecap, and the only cause I can think of is leaning on it (on carpet) for a couple of minutes while brushing dd's teeth. There's no way that that should cause a bruise, and yet it first started hurting right after that. My shoulder is also bugging me like it's bruised on the inside. The only reason I can come up with is from sleeping with it around dd - like I do all.the.time with no trouble like this.

Also, my face is breaking out in nodular acne. I used to have bad acne in high school, nothing touched it but accutane, and then it was only like 95% gone after flaring HORRIBLY. Since being pg and nursing, it's been close to 100% gone. After the NAC incident, I've had a bit, but it hasn't been painful nodular stuff like this. I'm wanting to blame the taurine, but all my googling is saying that it should make acne go away, not appear. So what's up?

No taurine yesterday or today. No improvement yet, either. I can't decide if I should start up again cause it *can't* be that or if I should take an extended break because so far every non-vitamin supplement has backfired on me :

I want to add taurine to increase bile and also to boost Magnesium absorption, but is it okay to use when I already suppect CBS upregulation? or it will add to total sulfur load? I do supplement with Molybdenum and it makes a huge positive impact when it comes to dealing with sulfur in foods. So at this point is it wise to add Tuarine or not?

[neveryoumindthere]

I so want to do molybdenum, but I said I wouldn't buy any more supplements!
for now i guess all i can do is increase my kelp and sesame seed paste

what other differences do you feel, coolgirl?

[Theloose]

Originally Posted by coolgirl

I want to add taurine to increase bile and also to boost Magnesium absorption, but is it okay to use when I already suppect CBS upregulation? or it will add to total sulfur load? I do supplement with Molybdenum and it makes a huge positive impact when it comes to dealing with sulfur in foods. So at this point is it wise to add Tuarine or not?

I'm not completely sure, but I think taurine uses a different pathway than the Mo/B6 sulfoxidation. So in theory, it should be a good thing. If you do add it, let us know how it goes! I've read that it can help with bowel tolerance for magnesium. If it does, I'm all ears In the mean time, I really need to keep up with the bone broth...

[Theloose]

I've been thinking on it. I'm wondering if adding taurine was enough to boost my cysteine levels, but not enough to actually make a difference with the calcium ion channels. I'm thinking more taurine might be in order...

Still no leads on the joints/bruising, though, and that one scares me more. I don't want to destroy my shoulder! I wonder if there's any chance it has to do with some sort of a healing/tightening up process? Hmm... maybe it's sore because I slept with it in a position that used to be normal, but with tighter ligaments, it stretched it funny? I kinda like that theory, but then it still leaves my poor bruised knee...

I really *want* the taurine to be a major key/shortcut for the glutamate stuff, and there aren't really any reported adverse effects. But...

Oh, and I want to update on my B5 deficiency theory - what if the B5 deficiency wasn't actually a deficiency at all? What if it's just that my cysteine was/is being put in the wrong places because of glutamate and so it requires high doses of B5 to 'pull' the cysteine back to coA? Cause then I acn blame that on folate deficiency too

Which brings me to... the folapro seems to be working its magic, but not quite as well as the lentils. I might have been getting more with the lentils, though. Next, I want to figure out the copper thing so I can hopefully get rid of the lentils/reflux problems and get back to food folate and other nutrients.

So taurine, zinc, vitamin C. Working on it!

[coolgirl]

Originally Posted by neveryoumindthere

I so want to do molybdenum, but I said I wouldn't buy any more supplements!
for now i guess all i can do is increase my kelp and sesame seed paste

what other differences do you feel, coolgirl?

Before adding Mo I was never able to take epsom salt baths, itching was really bad and also now I can enjoy eggs and dairy freely..

[mommyabroad]

Originally Posted by neveryoumindthere

nak
Are you off gluten by any chance. the above bolded stood out for me b/c i was the same ..dealt with low iron my whole life until i went off gluten last yr.within weeks my iron was awesome with no supplementation

--Yes, off of gluten completely -- including oats. I was still doing oats in the fall/winter -- wonder if that's why they dropped?

[Theloose]

Just noting for later...

"The herb Yucca, Dr. Yasko’s Ammonia support RNA product, and supplementation with charcoal and carnitine will bind up or neutralize ammonia, and add to your dietary efforts."
http://heartfixer.com/AMRI-Nutrigenomics.htm

Carnitine for detoxing ammonia
http://www.ionchannels.org/showabstr...?pmid=12602515

[coolgirl]

Originally Posted by whoMe

Just noting for later...

"The herb Yucca, Dr. Yasko’s Ammonia support RNA product, and supplementation with charcoal and carnitine will bind up or neutralize ammonia, and add to your dietary efforts."
http://heartfixer.com/AMRI-Nutrigenomics.htm

Carnitine for detoxing ammonia
http://www.ionchannels.org/showabstr...?pmid=12602515

Lately, I had been thinking about controlling ammonia so tried Yucca but got lot of gas of just using 1/8 of capsule, so I am leaning towards Carnitine but which one Acetyl-l-carnitine or l-carnitine??

[coolgirl]

Low Bh4

Just read at dr. yasko site -"Royal Jelly is a nice natural source of BH4 but is not good for those with bee sensitivity and it is also quite low dose."

Just curious ---Has any one tried it??

[Theloose]

Royal jelly is also high in pantothenic acid, iirc. I'll have to check that out! I don't know about forms of carnitine. I want to actually get my ammonia levels checked before adding even *more* random amino acids I know nothing about

I want to look into what part of the yucca to use - I've got three trees in my back yard

[Theloose]

Alright, Jacqueline, I'm finally hooked into the purines. How long did it take?

Guanosine triphosphate (GTP) is the precursor to BH4. But I bet you knew that already Off to learn more...

[lil_miss_understood]

Originally Posted by whoMe

Alright, Jacqueline, I'm finally hooked into the purines. How long did it take?

Guanosine triphosphate (GTP) is the precursor to BH4. But I bet you knew that already Off to learn more...

Yeah and there's a really long and horribly self-defeating process (creates ammonia as a byproduct, among other things I'm sure) by which it can be created from adenosine rather than guanosine.

[Theloose]

And who knew biotin helps protect against ammonia toxicity!?

Everything in me can now be closely linked to folate deficiency/high ammonia. Wow.

[coolgirl]

Originally Posted by whoMe

Royal jelly is also high in pantothenic acid, iirc. I'll have to check that out! I don't know about forms of carnitine. I want to actually get my ammonia levels checked before adding even *more* random amino acids I know nothing about

I want to look into what part of the yucca to use - I've got three trees in my back yard

I am not aware of any test that is targeted towards ammonia levels; however, urine amino acid is best indicator of methylation as it shows which pathways are over or under active.

[coolgirl]

Originally Posted by whoMe

And who knew biotin helps protect against ammonia toxicity!?

Everything in me can now be closely linked to folate deficiency/high ammonia. Wow.

Biotin is high in sulfur and just wondering if you suspect CBS up regulation then shouldn't you be avoiding biotin?

[lil_miss_understood]

Originally Posted by coolgirl

Biotin is high in sulfur and just wondering if you suspect CBS up regulation then shouldn't you be avoiding biotin?

What does CBS up regulation have to do with high sulfur? Or am I interpreting that wrong?