Originally Posted by New Mama
Do you think if the father has a MTHFR mutation that could contribute to Down syndrome, or is it just the mother?
My DH's daughter from his first marriage (the third of his first three kids, born when he was 28 and his then-wife was 29) has DS. I know that *I* have a MTHFR mutation (and our son was born with a sacral dimple) but I couldn't get DH's doctor to test him for it. I know his ex-wife has a lot of low-level health issues & I wouldn't be surprised if she had a mutation, too, though.
If you look at my family, everyone on my father's side has the face structure associated with tongue tie. His mother, him, his brother, 3 of his 4 sisters, me, and my little sister.
My mother probably had low folate when pregnant. She was on birth control pills for a decade. She also probably had low vitamin D from working long hours indoors all year long. Good thing she always ate decently. Real foods, though not raw or organic or grass fed or unpasteurized etc.
So, what I figure is that the MTHFR variation comes from my father, and the nutritional conditions come from my mother.