Originally Posted by ema-adama
Do you have any thoughts on how a study could be designed that would at least start looking at the other side of the impact of vaccines beyond triggering an immune response to develop antibodies without the clinical disease?
I think one thing that needs to happen is that we need to clear about what question such a study is supposed to answer. For me there are two important questions....
1). Does the current vaccination policy save more harm than it causes?
2). Given the current vaccination policy, does vaccinating my child increase or decrease the risk of something bad happening to my child?
I think the first question may not be definitively answerable, the second one is tricky and hugely time consuming, but I think probably is answerable.
One of the problems as I see it is defining sufficiently accurately what we mean by harm/something bad. Do we mean hospital admissions? Do we mean just death? Do we mean any condition in a list that we all agree in advance. Right now there seems to be a lot of debate as to what the harm is that we should be looking for, so I don't think this is a trivial thing to define at all.
What questions would you want the study to answer?