Yes, my youngest is a special needs child with a primary immune deficiency. He has a chronically low t-cell count from an underdeveloped thymus gland. Because of that, he is unable to hold immunity to viral infections, and it takes him a long LONG time to fight off a virus. He also is very prone to secondary bacterial infections because of the length of time and the effort involved in fighting off viral infections. He also has several malformations of his airway which makes him prone to airway illnesses.
Yes, the decision on vaxing him was very hard. We are stuck in a catch 22 of sorts, because he is one of the kids who could truly benefit from vaccinating, but yet because of his particular immune deficiency, he likely wouldn't be able to build any immunity from the vaccine anyway.
I WANT to vaccinate him for pertussis and flu, but after talking myself into circles dozens of times (many of those times in various threads on this forum!) I've come to the same decision. It's not worth the risk. The risk for him is that it won't work, PLUS all the risks of the vaccine itself, so I'm taking on the risk of vaccine side effects for basically no potential of any benefit to him. It doesn't make sense for us.
He did receive RSV immunoglobulin throughout his first RSV season, it's not quite a vaccine in the traditional sense of the word, it was an immunoglobulin given every 28 days. He still got RSV that season, but avoided being hospitalized. He also got RSV this season, he didn't qualify for the immunoglobulin because of his relative stable health. He has been hospitalized this winter for rotavirus, which is a vaccine he's not a candidate for anyway because it's live-virus. He's also not a candidate for MMR or CP or flumist.
It is extremely difficult knowing that my child really COULD die from what would otherwise be relatively minor for most children. So it was a more heart wrenching decision yes.