Mothering › Forums › Health › Vaccinations › Waning immunity
New Posts  All Forums:Forum Nav:

Waning immunity

post #1 of 17
Thread Starter 
Can you help me fill the blanks?

I would like to know how long, for how many years each vax gives the average person immunity.

Hib
DTaP
IPV

MMR

Thanks!!
post #2 of 17
I don't know that studies have examined that. I do know that many women (including myself) do not show immunity to rubella when prenatal blood work has been taken.

I was "up to date" on vaccines per the childhood schedules from the mid '80s and had gotten an extra MMR 8 years before my prenatal blood work was done.
post #3 of 17
Quote:
A review of the published data on duration of immunity reveals estimates that infection-acquired immunity against pertussis disease wanes after 4-20 years and protective immunity after vaccination wanes after 4-12 years.
http://www.ncbi.nlm.nih.gov/pubmed/15876927


For rubella, you are going to find conflicting information. Some studies that are looking at 15 year periods are looking at people who had only one dose. The only 15 yr study I have been able to find with 2 doses given at childhood was this one:

http://www.sciencedirect.com/science...9399f4959c1f13


I have this on tetanus immunity length:

Quote:
Conclusions Despite the fact that effective vaccines against tetanus have been available since the 1940s, many Americans do not have immunity to tetanus, and the rates are lowest among the elderly. There is an excellent correlation between vaccination rates (96 percent) and immunity (96 percent) among six-year-olds. However, antibody levels decline over time, and one fifth of older children (10 to 16 years of age) do not have protective antibody levels.
http://content.nejm.org/cgi/content/abstract/332/12/761


I'll see what I can find on IPV, but, from what I have read, it is long lasting.
post #4 of 17
The duration of immunity for most diseases is going to depend on how much circulation of the wild pathogen is around. For example, if you got the MMR when measles was still fairly endemic, then running into someone shedding measles virus would act as a natural vax booster. So for most diseases, it's really unknown how long vax immunity will last.
post #5 of 17
Quote:
Originally Posted by mamakay View Post
The duration of immunity for most diseases is going to depend on how much circulation of the wild pathogen is around. For example, if you got the MMR when measles was still fairly endemic, then running into someone shedding measles virus would act as a natural vax booster. So for most diseases, it's really unknown how long vax immunity will last.
Wait a sec...doesn't that mean that measles "eradication" is not a goal to aspire to?
post #6 of 17
Quote:
Originally Posted by kidspiration View Post
Wait a sec...doesn't that mean that measles "eradication" is not a goal to aspire to?
That depends on how ok one is with the idea of a possible lifetime of boosters.
If everyone gets the MMR every 5 or 10 years, it won't matter.
Measles can be eradicated globally, I think, but it will take a lot more than 2 shots per person to make it happen, IMO.
post #7 of 17
But what really irks me is the fact that this was never what we signed up for. Contrary to provax misinformation, people weren't begging for a measles vax; they had to be wooed into vaxing their kids for measles, with a promise of "Just let us give your kid this one shot, and by the end of the summer, the whole vaccination thing will be over". People who had HAD measles themselves and seen all their siblings get it and all their friends get it had to be persuaded to vax their kids with false promises.

Measles is relatively deadly compared to some modern "VPDs", but the vax is not "a victim of it's own success". That is a total lie.
I really wonder what people would have thought in the 60's if they were handed the info we know now, and asked to make a decision about if this was something they really wanted to do.
Just like if parents in the mid 90's were told "Ok, we're going to give your kid a chickenpox shot, but you're going to have to give another dose, and probable another one later because vax immunity is short lived, and vaxing all these kids will make older kids more likely to catch CP and get sicker because they're older, and be at an increased risk of complications and death, and then we're going to give all the older adults Zostavax, because vaxing the kids will make adults have shingles more often, which can also result in extreme pain and sometimes death."
How many people would think this was a great idea and give informed consent to vax for that scenario?
post #8 of 17
Thread Starter 
NAK

so wait a minute.

no one knows for sure how long immunity from vaxes lasts? not even average # of years?

why aren't doctors in developed and western countries hounding adult patients to get their boosters? why NOT send out booster reminder letters if they are so darn impt to protect the herd???? i don't understand ...
post #9 of 17
Quote:
Originally Posted by Spectrolite View Post
NAK

so wait a minute.

no one knows for sure how long immunity from vaxes lasts? not even average # of years?

why aren't doctors in developed and western countries hounding adult patients to get their boosters? why NOT send out booster reminder letters if they are so darn impt to protect the herd???? i don't understand ...

They are starting to do this.
post #10 of 17
Thread Starter 
I have heard about them pushing the pertussis vax for adults, but what about the others?
And why only NOW??
post #11 of 17
Quote:
Originally Posted by Spectrolite View Post
I have heard about them pushing the pertussis vax for adults, but what about the others?
And why only NOW??
Well, until recently, all the diseases were still circulating, so the vaccine immunity was getting naturally "boostered". So there was really no need to get more boosters from a shot.
So now that (for example) measles is eliminated, they don't know if adults are going to stay immune or not.

Here's an article about it:

http://insidevaccines.com/wordpress/...d-of-the-herd/


http://www.medbroadcast.com/health_n...hannel_id=1000
post #12 of 17
Quote:
Originally Posted by mamakay View Post
The duration of immunity for most diseases is going to depend on how much circulation of the wild pathogen is around.
This is especially true for rubella. Most adult women who have immunity had it due to a secondary infection with the wild virus.

http://www.ncbi.nlm.nih.gov/pubmed/4...?dopt=Abstract

Quote:
The high percentage of women with persistent rubella antibodies 15 years after vaccination might be explained in part by the presence of subclinical reinfections due to a wild rubella virus.
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

Quote:
Although the model predicts elimination of the rubella virus, data show that virus circulation is still present at a higher level than expected by the model.
http://www.ncbi.nlm.nih.gov/pubmed/1...?dopt=Abstract

Quote:
Subclinical infection is not uncommon after all three vaccines. Where measles is concerned, immunity may possibly be regarded as a continuum which, depending upon the antibody level, protects the individual from various degrees of clinical disease. If wild virus can be spread via individuals with subclinical infections, it is doubtful whether population immunity (herd immunity), which is necessary to eliminate the three diseases, can be attained in large populations.
And of course some vaccines shed which pretty much blows the theory of herd immunity -

http://insidevaccines.com/wordpress/...cine-shedding/



Quote:
Originally Posted by Spectrolite View Post
I have heard about them pushing the pertussis vax for adults, but what about the others?
And why only NOW??
This generation of parents is ready to receive vaccines for themselves. because most of them had been vaccinated as children and see nothing wrong with the vaccine program.

My generation, on the other hand, was raised with childhood diseases and saw nothing wrong with them. So we were not so quick in jumping on the band wagon of a vaccine program.
Most of us saw no reason to vaccinate for measles much less chicken pox.
post #13 of 17
Quote:
Originally Posted by Spectrolite View Post
I have heard about them pushing the pertussis vax for adults, but what about the others?
And why only NOW??
The focus was on pediatric population for so long, now the vaccination focus has shifted to the adolescent population with Gardasil, Menactra and TDaP... its only a matter of time before adults become the prime target.
post #14 of 17
Quote:
Originally Posted by Jugs View Post
The focus was on pediatric population for so long, now the vaccination focus has shifted to the adolescent population with Gardasil, Menactra and TDaP... its only a matter of time before adults become the prime target.
Actually they want to make money off our body and blood from cradle to grave.
post #15 of 17
^^For sure. Its just that adult vaccinations kind of got back-burnered during the influx of pediatric vaccines. At some point there will be a more aggressive adult vaccintion campaign, as the first heavily-vaccinated generation is reaching adulthood, cmplete with wanning immunity and a general acceptance of vaccination.
post #16 of 17
Quote:
Originally Posted by Jugs View Post
^^For sure. Its just that adult vaccinations kind of got back-burnered during the influx of pediatric vaccines. At some point there will be a more aggressive adult vaccintion campaign, as the first heavily-vaccinated generation is reaching adulthood, cmplete with wanning immunity and a general acceptance of vaccination.

It's already underway......
Quote:
U.S. Adults 'Needlessly Vulnerable' to Vaccine-Preventable Diseases, According to New Report
http://www.prnewswire.com/ (type vaccination in the search box)

Quote:
Vaccines are as crucial to our long-term health as are screenings for certain cancers. Unfortunately, many adults associate vaccinations with childhood, or assume influenza is the only vaccine they need," said William Schaffner, MD, President-Elect of NFID and chairman of the Department of Preventive Medicine at Vanderbilt University School of Medicine. "Vaccines are currently available to protect adults against many serious illnesses, but they are significantly under-used, elevating the risk of illness and even death."
Quote:
To help educate the public, healthcare providers and the media, NFID launched a new comprehensive Web site on the importance of adult vaccination at www.adultvaccination.com. The Web site includes critical information on 13 adult diseases and the vaccines recommended to protect against them. The Call to Action also is available for download on the Web site.
The last line is my favorite though
Quote:
NFID's adult immunization initiative is made possible through unrestricted educational grants to NFID from GlaxoSmithKline, Merck, sanofi pasteur and Wyeth Pharmaceuticals.
(bolding mine)
post #17 of 17
Repeat 10 times:

VACCINES ARE NOT PROFITABLE

Thank you.
New Posts  All Forums:Forum Nav:
  Return Home
  Back to Forum: Vaccinations
Mothering › Forums › Health › Vaccinations › Waning immunity