Part I is at detox pathway guinea pig
That thread is getting too long, and it's not so helpful that way. Too many wrong turns to weed through.
Here's the cliff notes version:
I'm trying to heal my daughter and my food sensitivities by opening our liver detox pathways nutritionally.
My MTHFR genes say I need to get lots of food folate, and avoid folic acid in supplements (and fortified foods). By replacing my B complex with individual B's plus food folate (in the form of lentils), I saw HUGE differences in myself and dd (for the better of course!). Those differences revolve around increased BH4 levels and increased methyl groups. But then I realized that the lentils were giving me reflux and I couldn't stomach that much chicken liver. Now I know that french green lentils are fine, but other green lentils aren't (they look totally different).
I ordered some folapro to keep up with the folate while figuring out food sources, but I think I used up our molybdenum stores. Folate and molybdenum and purines are involved in making new BH4.
Meanwhile, I was getting dependant on pantothenic acid (B5) to support my adrenals. With some brainstorming help, I realized that I had created a deficiency in cysteine by supping so much B5. Now I increase my mag when my adrenals are slipping and keep the B5 constant.
In this whole process, I tried some detox supplements, but only got negative results (hairy tongue from NAC and lots of congestion from MSM) and came to the conclusion that our calcium ion channels are stuck open. I was thinking that would be due to eating lots of protein (meat) resulting in high ammonia that increases glutamate levels, which holds open Ca channels. But then I got a blood test back showing normal serum ammonia. Now I'm left wondering if that was the right test, or if I need to be searching out a different explanation. One other explanation is high levels of active vitamin D, due to low calcium intake. This one fits us pretty well, and so I'm actively working on getting us lots of bone broth - though I want to know just how much calcium is in there!
The latest part of the journey is teaching me about EFAs and how they make prostaglandins, which turn inflammation on and off. I have not been taking CLO, so I have decided it's time to start. Mostly for the EPA, but I'm happy to increase our A and D at the same time.
So where am I now? I'm at a huge life turning point. There's a lot going on IRL that I'm not going into here, but suffice it to say that it's time for me to stop leaning on supps so much, and it's time to focus on foods. I'm starting this thread in hopes that you all will help me figure out how to make that transition


That thread is getting too long, and it's not so helpful that way. Too many wrong turns to weed through.
Here's the cliff notes version:
I'm trying to heal my daughter and my food sensitivities by opening our liver detox pathways nutritionally.
My MTHFR genes say I need to get lots of food folate, and avoid folic acid in supplements (and fortified foods). By replacing my B complex with individual B's plus food folate (in the form of lentils), I saw HUGE differences in myself and dd (for the better of course!). Those differences revolve around increased BH4 levels and increased methyl groups. But then I realized that the lentils were giving me reflux and I couldn't stomach that much chicken liver. Now I know that french green lentils are fine, but other green lentils aren't (they look totally different).
I ordered some folapro to keep up with the folate while figuring out food sources, but I think I used up our molybdenum stores. Folate and molybdenum and purines are involved in making new BH4.
Meanwhile, I was getting dependant on pantothenic acid (B5) to support my adrenals. With some brainstorming help, I realized that I had created a deficiency in cysteine by supping so much B5. Now I increase my mag when my adrenals are slipping and keep the B5 constant.
In this whole process, I tried some detox supplements, but only got negative results (hairy tongue from NAC and lots of congestion from MSM) and came to the conclusion that our calcium ion channels are stuck open. I was thinking that would be due to eating lots of protein (meat) resulting in high ammonia that increases glutamate levels, which holds open Ca channels. But then I got a blood test back showing normal serum ammonia. Now I'm left wondering if that was the right test, or if I need to be searching out a different explanation. One other explanation is high levels of active vitamin D, due to low calcium intake. This one fits us pretty well, and so I'm actively working on getting us lots of bone broth - though I want to know just how much calcium is in there!
The latest part of the journey is teaching me about EFAs and how they make prostaglandins, which turn inflammation on and off. I have not been taking CLO, so I have decided it's time to start. Mostly for the EPA, but I'm happy to increase our A and D at the same time.
So where am I now? I'm at a huge life turning point. There's a lot going on IRL that I'm not going into here, but suffice it to say that it's time for me to stop leaning on supps so much, and it's time to focus on foods. I'm starting this thread in hopes that you all will help me figure out how to make that transition











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: I hide 1/2 pkg of B&E chicken livers in my meatloaf and it gives it a really nice taste
) and it is delish. DD thinks it's just ok, but she'll have a couple little bites. 