My children have a life-threatening blood disease. My two oldest sons are from my first marriage and were sick as children much more than my youngest son. My youngest son is from my second marriage. It is a rare disease and the immunologist thinks my son may have had a transient form.
The thing is if you survive 20 years, only 64% do, then you get very sick when you are around 30 and have to have exensive, awful IVs every 3 weeks the rest of your life and may not be able to work. The older two are 29 and 26. I've been having IVs for 21 years and can't work. It makes the whole transplant issue a lot more personal. My one son has had a baby and he wasn't a match for me or my sons.
The song Carry You Home by James Blunt was a great choice for the movie.