Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy

[MaryJaneLouise]

I ran across this abstract from PubMed (mainstream medical journals) and thought some here might be interested:

Acta Paediatr. 2009 Jun 1.
Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy.

Furuhjelm C, Warstedt K, Larsson J, Fredriksson M, Böttcher MF, Fälth-Magnusson K, Duchén K.

Division of Pediatrics, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.

Maternal intake of omega-3 (omega-3) polyunsaturated fatty acids (PUFAs) during pregnancy has decreased, possibly contributing to a current increased risk of childhood allergy. Aim: To describe the effects of maternal omega-3 long-chain PUFA supplementation during pregnancy and lactation on the incidence of allergic disease in infancy. Methods: One hundred and forty-five pregnant women, affected by allergy themselves or having a husband or previous child with allergies, were included in a randomized placebo-controlled trial. Daily maternal supplementation with either 1.6 g eicosapentaenoic acid and 1.1 g docosahexaenoic acid or placebo was given from the 25(th) gestational week to average 3-4 months of breastfeeding. Skin prick tests, detection of circulating specific immunoglobulin E (IgE) antibodies and clinical examinations of the infants were performed. Results: The period prevalence of food allergy was lower in the omega-3 group (1/52, 2%) compared to the placebo group (10/65, 15%, p < 0.05) as well as the incidence of IgE-associated eczema (omega-3 group: 4/52, 8%; placebo group: 15/63, 24%, p < 0.05). Conclusion: Maternal omega-3 fatty acid supplementation may decrease the risk of food allergy and IgE-associated eczema during the first year of life in infants with a family history of allergic disease.

IOW, those who took the fish oil supplement, only 1 out of 52 babies had food allergies with their clinical tests, vs 10 out of 65 babies who DIDN'T take fish oil.

For eczema, only 4 out of 52 in the fish oil group were affected, vs 15/63 in the no fish oil (placebo) group.

This was in a treatment group with family history and/or previous birth children with allergies.

[MaryJaneLouise]

[Chinese Pistache]

I definitely think fish oil is important. It didn't make my baby allergy-free though, but I do think everyone should take it (or eat fish) for general health.

[ASusan]

Originally Posted by Chinese Pistache

I definitely think fish oil is important. It didn't make my baby allergy-free though, but I do think everyone should take it (or eat fish) for general health.

I agree. It's unfortunate that we're in the 2% group who consumed omega-3s and ended up with eczema.

[Chinese Pistache]

Originally Posted by ASusan

I agree. It's unfortunate that we're in the 2% group who consumed omega-3s and ended up with eczema.

Yeah, I guess that the ladies whose kids didn't end up with eczema aren't reading this forum