Okay, my vitamin vs minerals theory (it gets kinda rambly watch out):
In my own experience, needs for some vitamins can keep going up and up, unless you find the cofactor that goes along with it. I think my whole pantothenic acid saga is in the detox pathway guinea pig
thread. I'm currently needing quantities of vitamins that are significantly higher than what you could ever get from food, and I don't think it's just the supplement form not being as available.
So I have this concept floating around in my head, but haven't figured out a good visual/description yet. Basically, we can use high doses of things to pull certain reactions in the body in the direction we want them to go. But our bodies are *supposed* to be handling the balance on their own - which means we're depleting *something* by taking higher and higher amounts. The goal is to get everything in the right ratios so we don't *need* to supplement and create that pull.
The minerals seem to be big regulators - calcium lowers the activated vit d, which closes ca ion channels, prevents lead absorption, and more. Mag help you use the calcium, helps close ca ion channels, takes some burden off of taurine production, and is required for so many enzymes. Those enzyme are what we're shifting around the balance of with the high dose vitamins.
Then there are the trace minerals - things like molybdenum for sulfur and chromium for insulin and iodine for thyroid and hormone regulation and...
And most of the vitamins need to be replaced on a day-by-day basis. It's hard to *really* have a long term deficiency that takes a while to correct. Versus the minerals, which are stored in the body long term, and are building blocks for all these enzymes. It seems a lot easier to have a long term deficiency of those (even passed from mom), messing up how our bodies regulate the rest of the good stuff. My intuition is saying that having good mineral levels acts as a buffer of sorts, so that the fluctuations in vitamins don't have so much of an impact. Especially for our situation.
I *know* that I have a lot of trouble getting in enough of the big minerals like calcium and magnesium. My morning sickness severity seems to be closely linked to how much calcium I'm getting, as well as my blood sugar. As in, the calcium seems to help stabilize my blood sugar so there aren't giant swings. Alternatively, I could try high dose B6 to block hormone receptors or...
Which reminds me, I might be a convert to solaray calcium hydroxyapatite instead of bone meal. maybe. It's essentially refined bone meal in a capsule. Hopefully in theory there's less risk of heavy metals (want to check that) and it's a much finer, blander powder. Disappears into a spoonful blackberry applesauce, especially with a layer of unadulterated stuff on top
And the perque chewable multis appear to be a go, *if* dd gets a whole (adult dosage) one. I think we'll be doing them every other day...