This is probably going to be long so apologizing in advance.
As the title says, I'm 39 (40 in March) and so is my dh. I have 3 live children and have had at least 4 miscarriages. I was diagnosed with PCOS in January 2002 while ttc ds2. I was diagnosed with the MTHFR double mutation in June 2006 while ttc ds3 after 3 early m/cs. I took 1500 mg metformin, low dose aspirin and used progesterone suppositories while ttc ds2 and ds3.
I had a 4th miscarriage in July at 11w. We weren't ttc (actually tta) so I wasn't taking anything for PCOS or m/c before I got pg. I did see a doc when I found out I was pg in May and discussed all of that. He said that since I had gotten pg without metformin I didn't need it. I had started taking the aspirin on my own. He tested my progesterone. It was 14.8. He said that was good so I didn't need progesterone. I know that's above the minimum but it still seems low to me, especially since I did m/c. I didn't m/c until 11w but my baby died at about 8w. I didn't have any spotting so it didn't look like a progesterone problem but I don't know. I tried to have chromosomal testing done but was told they weren't able to get enough cells to get any good results. So, I have no idea why I m/ced this time (not that I have any definitive answers for the other ones).
My dh is coming home soon from a deployment. We will have not quite a month together before he has to leave for another 5-6 months. I basically have one shot to get pg again, assuming that I ovulate while he's home. I have long, irregular cycles so I can't plan with any kind of certainty when I will be fertile. I've decided I should take progesterone this time regardless of whether or not my #s are good. I'm wondering if I should arrange to have progesterone suppositories ahead of time since they'll need to be made, which takes at least 3 days, if I remember correctly, or if I should just plan to call the doc if I get a + hpt and have him call in a script for progesterone pills. I test (and get +) very early, 7-10dpo. I've never used the pills so I don't know how well they work, if they cause stomach problems, etc. I have a very sensitive stomach. I can't even take vitamin supplements because they make me extremely nauseous. Anyone have an opinion on whether or not there's a significant difference in the efficacy of the pills vs. the suppositories? Also, how bad are the pills at causing nausea?
Secondly, I don't know if I should start taking metformin again. The last 2 times I had my blood sugar tested it was normal so the docs told me I didn't need it. I'd prefer not to take it. I'm breastfeeding my 2yo and have concerns about how it might affect his natural blood sugar regulation. OTOH, I'd rather take it than not if it'll keep me from having another m/c. I just don't know what to do about that.
One more qeustion. On the low dose aspirin, I can't remember when to start taking it. Do you start as soon as AF is over and take it the entire cycle or do you not start taking it until after you O?
As the title says, I'm 39 (40 in March) and so is my dh. I have 3 live children and have had at least 4 miscarriages. I was diagnosed with PCOS in January 2002 while ttc ds2. I was diagnosed with the MTHFR double mutation in June 2006 while ttc ds3 after 3 early m/cs. I took 1500 mg metformin, low dose aspirin and used progesterone suppositories while ttc ds2 and ds3.
I had a 4th miscarriage in July at 11w. We weren't ttc (actually tta) so I wasn't taking anything for PCOS or m/c before I got pg. I did see a doc when I found out I was pg in May and discussed all of that. He said that since I had gotten pg without metformin I didn't need it. I had started taking the aspirin on my own. He tested my progesterone. It was 14.8. He said that was good so I didn't need progesterone. I know that's above the minimum but it still seems low to me, especially since I did m/c. I didn't m/c until 11w but my baby died at about 8w. I didn't have any spotting so it didn't look like a progesterone problem but I don't know. I tried to have chromosomal testing done but was told they weren't able to get enough cells to get any good results. So, I have no idea why I m/ced this time (not that I have any definitive answers for the other ones).
My dh is coming home soon from a deployment. We will have not quite a month together before he has to leave for another 5-6 months. I basically have one shot to get pg again, assuming that I ovulate while he's home. I have long, irregular cycles so I can't plan with any kind of certainty when I will be fertile. I've decided I should take progesterone this time regardless of whether or not my #s are good. I'm wondering if I should arrange to have progesterone suppositories ahead of time since they'll need to be made, which takes at least 3 days, if I remember correctly, or if I should just plan to call the doc if I get a + hpt and have him call in a script for progesterone pills. I test (and get +) very early, 7-10dpo. I've never used the pills so I don't know how well they work, if they cause stomach problems, etc. I have a very sensitive stomach. I can't even take vitamin supplements because they make me extremely nauseous. Anyone have an opinion on whether or not there's a significant difference in the efficacy of the pills vs. the suppositories? Also, how bad are the pills at causing nausea?
Secondly, I don't know if I should start taking metformin again. The last 2 times I had my blood sugar tested it was normal so the docs told me I didn't need it. I'd prefer not to take it. I'm breastfeeding my 2yo and have concerns about how it might affect his natural blood sugar regulation. OTOH, I'd rather take it than not if it'll keep me from having another m/c. I just don't know what to do about that.
One more qeustion. On the low dose aspirin, I can't remember when to start taking it. Do you start as soon as AF is over and take it the entire cycle or do you not start taking it until after you O?
My test results were never positive for high blood sugar. Once or twice I was borderline so I was given metformin just in case only because we were ttc. I know it's supposed to reduce the higher risk of m/c in women with PCOS but since there's always been some question about whether or not I really needed it I decided not to take it since we aren't ttc. 3 of my 4 m/cs occurred while I was taking met.
