pregnant, nursing 2, Hale lookup?

[thixle]

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Edited by thixle - 6/16/11 at 5:05pm

[Juvysen]

I have no idea, but I wanted to offer

I know our local LLL leader had a big book of "breastfeeding safe" medications... maybe try calling your local leader and ask about the specific drugs?

[D_McG]

http://neonatal.ttuhsc.edu/discus/messages/52/3718.html

[Flower of Bliss]

I'm sorry you are facing this decision, especially with your marriage seeming unstable. I'm sending you love, light, and strength as you make your decision.

According to Hale (2006 edition) Misoprotol is an L3. Here's a highlight of the text:

Secretion of misoprostol in milk is unlikely due to rapid maternal metabolism.  However, secretion of its active metabolite is possible and could produce diarrhea in newborns alothough this has not been reported. 


It looks like the link above covers the other drug well.

[mariekitt24]

I'm not here to flame, my heart goes out to you. but it also goes out to that precious baby inside you.. would it be possible for you to put the baby up for adoption instead? I think he or she would thank you down the road. I dont know anything about specific medications but I assume that any medications we take aren't exactly good for our children.

[thixle]

Thank you so much for the information.

And all the support makes it a little easier to get a breath. I knew I could count on MDC in a tough time

[StoriesInTheSoil]

Sending you love and light, mama. I hope you are able to find peace in whatever choice you make.

[hillymum]

I have no advise but wanted to offer hugs and sympathy. No matter what happens I hope your husband steps up and is supportive.

[annettemarie]

Just a reminder-- please keep to the breastfeeding advice the OP asked for. More personal conversations would best take place via PM. Thanks!

[TiredX2]

I am so sorry that you are facing this decision.

Just to make sure you got the info from the Hale's Link:

We do not have data on the transfer of RU-486(mifepristone) into human milk. That said, it has a steroid-like structure, it penetrates the CNS and amniotic fluid extremely poorly, and it is highly protein bound (98%). Thus I would guess that its transfer into milk would be minimal to virtually nothing.

Mifepristone is a potent inhibitor of the progestin receptor. Interestingly, it has actually be used in monkeys postnatally to stimulate milk production due to its effect on the progestin receptor. So I really doubt it would transfer significantly to a breastfeeding infant, nor would it likely produce side effects in such an infant even if it did.

Here is an older thread from MDC with a Momma looking for abortion information while bfeeding:

http://www.mothering.com/discussions...t=mifepristone

This seemed especially relevant:

Yes, you can. Mifepristone (RU-486) shouldn't require a pump and dump, because it's a progesterone blocker and doesn't have an effect on the baby though it does pass into breast milk. If you choose the methotrexate option, you do need to pump and dump for 24 hours. Misoprostol in both cases is fine.

Post #25 mentions the posibility of diahrea in the baby due to Misoprostol, but they were talking of an infant. This response in #26 addresses that concern:

We use misoprostol often for PPH and there's no effect that I've ever seen in the babies BF immediately afterward. The dosage for PPH is also much higher than is used for a medical AB. Thomas Hale's 2002 lists diarrhea as a theoretical risk of miso in infants, but quite honestly we generally don't even see it in the moms.

A 72 hour pump and dump for miso seems excessive, since it's frequently given in labor and postpartum with no pump and dump required.

Honestly, with the ages of your children I would not personally be concerned with those specific medications.

Please, take it easy on yourself no matter what you decide. Either way, this is a very hormonal, emotionally turbulent time and you need to take care of YOU while you take care of your little ones.

All the best

[porcelina]

I just want to say that I took misoprostol (cytotec) for a missed miscarriage, and it was horrible!! I bled for months, in the moment I took it I had hot flashes and felt a little insane. I have since read other stories of women with bad experiences. I think there may even be risks of uterine rupture. Please do not take the chemical route. Do what you have to do, but be careful.

[PatioGardener]

Originally Posted by TiredX2

Honestly, with the ages of your children I would not personally be concerned with those specific medications.

And any sedation/pain medication used with a surgical route would also likely be compatible with breastfeeding.


Sending you s