I got the rest of Connor's yearly immunology tests. Basically, he's low across the board in t-cells still, BUT as he ages the reference range is lowered so it's less of an impact on him.
CD3% Total T Cells, 57 (low)
CD3 Total T Cells, 2217 (low)
CD4 % Helper T Cells, 36 (low)
CD4 Total Helper Cells, 1406 (low)
CD8s were all in the normal range (suppressor cells) so that brought his helper/suppressor ratio up just barely into the "normal" range (1.84, range of 1.17-6.22)
Total B cells was 1172 (no range given?)
% B cells was 31 (no range?)
% natural killer cells was 10 (no range?)
ALL of his Mitogens were normal, most were 100, a few were in the 70s-80s, but that's considered normal.
His IgG was normal, IgA normal, and IgM was low (35, range 47-160).
SO...the dr said that he likes these numbers, that they portray a "mild" or "subtle" immune deficiency (versus the "moderate" he used to have). He said that we still need to be very aggressive about treating illnesses because he will still be more likely to become more sick and/or have complications from simple illnesses.
He said that still what's going on is that Connor's t-cell count is low, but function appears normal. Basically he doesn't have enough, but those that he does have are doing their jobs well. The b-cells appear normal, even though illness history suggests there might be some dysfunction.
The dr's guess is that any illnesses Connor has now are more likely caused primarily from his anatomy than from his underlying immune deficiency. So in other words, his physical malformations are putting him at higher risk of illness than his immune system is. Which still supports the guidance we've received to not put him "in a bubble"; just to take sensible illness precautions.
So...yay! Good to have good news! Everything is as we would expect with his syndrome.
CD3% Total T Cells, 57 (low)
CD3 Total T Cells, 2217 (low)
CD4 % Helper T Cells, 36 (low)
CD4 Total Helper Cells, 1406 (low)
CD8s were all in the normal range (suppressor cells) so that brought his helper/suppressor ratio up just barely into the "normal" range (1.84, range of 1.17-6.22)
Total B cells was 1172 (no range given?)
% B cells was 31 (no range?)
% natural killer cells was 10 (no range?)
ALL of his Mitogens were normal, most were 100, a few were in the 70s-80s, but that's considered normal.
His IgG was normal, IgA normal, and IgM was low (35, range 47-160).
SO...the dr said that he likes these numbers, that they portray a "mild" or "subtle" immune deficiency (versus the "moderate" he used to have). He said that we still need to be very aggressive about treating illnesses because he will still be more likely to become more sick and/or have complications from simple illnesses.
He said that still what's going on is that Connor's t-cell count is low, but function appears normal. Basically he doesn't have enough, but those that he does have are doing their jobs well. The b-cells appear normal, even though illness history suggests there might be some dysfunction.
The dr's guess is that any illnesses Connor has now are more likely caused primarily from his anatomy than from his underlying immune deficiency. So in other words, his physical malformations are putting him at higher risk of illness than his immune system is. Which still supports the guidance we've received to not put him "in a bubble"; just to take sensible illness precautions.
So...yay! Good to have good news! Everything is as we would expect with his syndrome.
