I've seen maps of chromosomes before, but this one is the most in-depth map I've ever seen! Holy cow!
http://www.ncbi.nlm.nih.gov/mapview/...=ideogr,g3,gb4[0.00%3A185.03]&ZOOM=100.0000
You can click on whatever chromosome you want to see, and you can click on a specific region to zoom in. It then has a list of genes associated with that region. You can further click on the links next to those genes and read about genomic sequences, registered disorders, etc etc etc...I don't even know half of what's here because I'm still trying to figure it out!! But I was so excited to find this in-depth information that I wanted to pass it on before I get lost in trying to decipher it all
The reason I went looking is because a relative of mine just got her microarray back and it's FULL of abberations! And only two of them were listed as "clinically significant":
7q11.22 deletion
16p11.2 duplication
Six others are listed as "no currently known clinical significance":
8p11.23 duplication
14q32.33 duplication
16p12.1 duplication
22q11.22 deletion
Xp22.33 deletion
Xp22.33 duplication
It was the 22q11.22 deletion that caught my eye, since my son has 22q11.2 deletion, which is a recognized syndrome with lots of complicated significance. So I was wondering why 22q11.22 is considered insignificant. Turns out that 11.22 is a small section of the 11.2 region, so her deletion is much smaller than my son's.
http://www.ncbi.nlm.nih.gov/mapview/...=ideogr,g3,gb4[0.00%3A185.03]&ZOOM=100.0000
You can click on whatever chromosome you want to see, and you can click on a specific region to zoom in. It then has a list of genes associated with that region. You can further click on the links next to those genes and read about genomic sequences, registered disorders, etc etc etc...I don't even know half of what's here because I'm still trying to figure it out!! But I was so excited to find this in-depth information that I wanted to pass it on before I get lost in trying to decipher it all
The reason I went looking is because a relative of mine just got her microarray back and it's FULL of abberations! And only two of them were listed as "clinically significant":
7q11.22 deletion
16p11.2 duplication
Six others are listed as "no currently known clinical significance":
8p11.23 duplication
14q32.33 duplication
16p12.1 duplication
22q11.22 deletion
Xp22.33 deletion
Xp22.33 duplication
It was the 22q11.22 deletion that caught my eye, since my son has 22q11.2 deletion, which is a recognized syndrome with lots of complicated significance. So I was wondering why 22q11.22 is considered insignificant. Turns out that 11.22 is a small section of the 11.2 region, so her deletion is much smaller than my son's.
