I make sure to do a little each day during the week and DH and I will do bigger stuff on the weekends. As long as I keep moving some and talk/sing some, I can usually wear my girl in a sling and do a lot and it keeps her entertained, so I usually try to have at least a 15-20 minute session of doing a bunch of stuff with her slinged, making sure to switch to something else (and then back later) if she starts getting bored with one thing. I can get quite a bit of laundry, dishes, spot cleaning (been using 7th Gen. stuff or just dish soap so that I don't worry about cleaning around her), general picking up, even vacuuming done this way. For anything that needs a good scrub for awhile, I wait until she is sleeping or DH can entertain her. And I will use her bouncy seat too, putting that in the middle of the kitchen floor or wherever, if she isn't in the mood for the sling.
I also try to get in another 15 minute cleaning/organizing bout after she goes to sleep for the first time at night. I don't get both of these in every night, but I make an effort to do so and it really helps keep things fairly well maintained. I do need to get better about the more deep cleaning stuff, it tends to get put off until we have guests over

I'd like to get a schedule going where I rotate through the deep cleaning stuff each weekend, but I'm not there yet.