I typically hand out the advice to keep it simple unless you run into a problem. I do a cold rinse first to keep stains at bay. Then a hot wash with 2 tbsp of detergent, and a cold rinse. And I'm done.
Once in a while, I'll use 1tbsp of detergent in a short cold wash, followed by a hot wash, and a cold rinse. I use non-sudsing detergent, so I don't do multiple follow-up rinses/washes.
I hang my covers and dry my flats, prefolds, fitteds, and AIOs in the dryer on regular.