I was so there a few months ago. Everything- the Zofran not working as well as it seemed to for everyone else (I puked on it many times), not wanting to take phenergan because of the side effects, the zantac for the constant reflux, the awful constipation even on Colace and prune juice to the point that I did enemas several times (mag citrate made me sick almost immediately, every time I tried).

I tried unisom and b6 from the start and never noticed HUGE relief from it, and it made me very sleep at first, but I will say having a constant, and I mean constant, low dosage of it in my blood at all times took a slight edge off. If I didn't keep up with every single dose on schedule, though, it was not helpful to take occasionally whatsoever. I don't think it would have been enough on its own anyway, but it might have prevented a bit of misery.

There's only so much you can do to control it. Sometimes, for some women, there isn't a miracle pill or a perfect answer that if you just did everything right, you'd feel so much better. Sometimes all you can do is keep hydrated and make it through one miserable day at a time. I hope you get the light at the end of the tunnel like I did- around 14-15 wks I was just about normal and now at 24 wks only certain smells bother me here and there, I can eat like normal again.