Originally Posted by ma2two
Where's the placebo? Side effects of Prevnar 13, the type and frequency, are compared to the old Prevnar vaccine. How can someone know whether the risks are acceptable to them, if the vaccine is not compared to a true saline placebo?
So, I thought I might work backward. Look at the safety studies of the old Prevnar vaccine. Guess what? The safety studies for the old Prevnar vaccine also did not use placebos. The controls in those studies were also other vaccines.
How in the world are we supposed to make informed decisions with this junk science?
This is common practice, not just with vaccines, but numerous medications and treatments during studies. In order to perform a study, you need the approval of the Institutional Review Board at that facility (be it a hospital, a clinic, a university, etc...).
It's considered unethical to deny a known beneficial therapy in order to have a perfect placebo. For example, if they were studying a new blood pressure medication, the placebo would be another blood pressure medication, because you're not allowed to deny the patient the known benefit by giving him a benign placebo.
If you look at other studies for other medications, you will find this is a very common practice.