I just doubt the numbers in the MMWR are accurate since not all jurisdictions report cases that aren't typed or those that are a type other than b.
post #121 of 150
7/4/10 at 12:00pm
| Virtually all cases of H. influenzae meningitis among children are caused by strains of type b |
| Nontypeable strains of H. influenzae commonly colonize the human respiratory tract and are a major cause of otitis media and respiratory mucosal infection but rarely result in bacteremic disease. |
| I don't have any links on hand, but I think someone mentioned in previous threads that with Hib gone, pneumoccocal took off. Anyone have any studies handy? And please anyone join in to correct me if I am wrong. I may have misremembered. |
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Is this one like other mainstream magazines, where every other page is an ad for some Big Pharma concoction?
Perhaps I'm picky, but I'd rather not take advice from magazines that feel no compunction about placing "health" articles between pharmaceutical ads. ![]() |
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Does anyone know why that happens? I give DD tylenol or motrin when she has a high fever (102ish)- should I not? Is there anything else I can do to help her fever- or is it not even something to worry about. (sorry, I know this is off topic..if someone would message me with the info or something, I would really appreciate it!)
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One of my fears (and I think it is shared by many Mom's on this board) is, when does it end? Can we really win this war against bacteria that for the most part, are normal human flora and don't cause disease except in rare cases? Are we doing more harm than good in the long-term? As seen on the ABC website, invasive diseases like meningitis are not going down in the population overall, but up.
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When I am debating with people about our decision to not vaccinate, this is one of the biggest arguments I hear and I'm never quite sure how to respond to it. Do we know this is true for a fact?
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Could you explain how this works with pertussis and tetanus specifically?
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Herd immunity applies only to communicable diseases. Tetanus is not contagious, or transmitted from person to person, and thus has nothing to do w/ herd immunity. A tetanus vaccine will protect an individual from a bacteria called Clostridium tetani, the spores of which are found in soils all around the world. When a spore enters even the smallest of cuts or abrasions in human skin, a toxin is produced that causes severe muscular spasms. This can lead to tetany, leading to lockjaw and eventually cessation of breathing (since the diaphragm is a muscle). The death rate is about 45% for those infected. The DTap vaccine protects against 3 separate diseases, one of which is tetanus; lifetime protection from tetanus requires booster shots, since immunity wanes over time.
Tetanus: http://emedicine.medscape.com/article/786414-overview Unlike tetanus, pertussis is a highly contagious disease (transmitted from person-to-person via respiratory transmission) & herd immunity applies. Pertussis, caused by a bacteria called Bordetella pertussis, is also protected by DTap. It is also known as "whooping cough", and symptoms include violent coughing, periods of apnea (non-breathing), vomiting, and sweating; complications after the disease include pneumonia, ear infections, weight loss, rib fracture, and even stroke in older adults. Though pertussis affects all age groups, the group of most interest in herd immunity are the infants/very young, very old, and immunocompromised; in other words, the most vulnerable people in our population. Pertussis in an infant is severe and often fatal, and the most common source of infection is from an unvaccinated mother or other family member. Immunity is very short-term, regardless if a person is vaccinated or acquires the disease naturally. There is an abundance information in the literature about the resurgence of pertussis due to the lack of booster shots; if the teens/adults in the population do not obtain booster shots or are partially immunized, they have ineffective immunity, leaving the most vulnerable members in a population at risk of serious illness, complications, and death. Pertussis: http://emedicine.medscape.com/article/967268-overview Infants/pertussis: http://emedicine.medscape.com/article/803186-overview The way herd immunity is determined within a given population for a given disease is via statistics & mathematics. There are computational programs that determine what % of people need to maintain up-to-date vaccinations in order to protect the rest of the population (ie. those who are unable to vaccinate for whatever reason, either health or personal reasons, and the young/infants, elderly, and immunocompromised). |
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exactly so you cannot apply herd innunity to a vaccine that doesn't prevent the transmission of the bacteria that CAUSES the disease.
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Exposure to a bacterial or viral invader stimulates the immune system to produce antibodies. These antibodies help recognize the invaders so that the immune system can quickly invoke an attack upon second or subsequent exposures to that same invader.
Vaccines induce this same antibody response, but with a benefit: with a vaccine, a person has an effective antibody response w/out having any prior natural exposure to the disease. This is b/c vaccines are either inactivated or dead pathogen (ie. the bacterial part contained w/in the vaccine can't cause disease, but it is recognized by the body as the disease-causing pathogen & thus induces an antibody response -- any second or subsequent exposure to the disease will cause a rapid & effective fight against the invader). Transmission is not prevented by a vaccine, for transmission will occur upon exposure. However, infection is prevented by the vaccine. Herd immunity applies to the percentage of people w/in a population who are protected from a disease. They are not "carrying around bacteria and passing it around". That would describe someone with active infection. People with an immunity to a disease do not have the disease, and they are not passing infection. Herd immunity means that the small subset of unvaccinated people within a population will not have exposure to a disease b/c there is no one around them carrying it. With reduced herd immunity, there is an increase number of people carrying the disease & exposing others. |
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exactly so you cannot apply herd innunity to a vaccine that doesn't prevent the transmission of the bacteria that CAUSES the disease.
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