Still... If it were just digesting food better, then skipping a meal would cause similar die off, wouldn't it? And why would that first tiny sprinkle be so painful? I like the pH idea, but haven't found a mechanism yet. I want to read more about trypsin and what other enzymes it activates. But first, there's life to keep up with.
I suppose here is as good a place as any to muse.
I added in the PNO a couple weeks ago. On average, I'm getting 1tsp, twice a day. At first there was the usual die off stuff. Now we're in no fun reaction land yet again. It's different symptoms, though - dd and ds are affected way more than me

and I can't put a finger on what it is. For dd, it's like she needs folate, or mag, or something. But is missing her usual low mag bedwetting and noise sensitivity. I think I've been too hopeful that we were close to the end, so I've been having fun with ferments (that I used to be able to eat in quantity, no prob) and playing with b12 drops (again, never noticed any b12 reaction, and consistently test good/high and don't have weird b12 genetics). Oh, and I just switched to a food based b complex. The current behavior is way too much for me, though, so I'm trying to get back to stable, but since I don't know what's causing it, its hard to know what to change. Whatever it is, now, rather than being waaaaaay too sensitive to what foods I eat, it seems I'm waaaaaay to sensitive to gut healing measures. I think that's progress, though?