Quote:
Originally Posted by Delicateflower 
Measles isn't injected intramuscularly, it's subcutaneous. But regardless, we know that both vaccines give good immune response and immunisation when given through the modes they are (intramuscular for one and subcutaneous for the other).
If you really want to be picky about mode of delivery and adequate immune response, how about polio? Delivering it the 'natural' way, through the mouth results in more side effects than the IM route.
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Yes, measles vaccine is an effective vaccine, although we don't know for how long. Pertussis less so, but an immune response is triggered through vaccination. There does seem to be a different quality to the immunity for vaccine induced immunity and acquired immunity in the community for Pertussis. It seems the innate immune system is more important than was realized when the DTP and subsequent DTaP were developed.
My point is that not all antigens are equal, and just because you are exposed to antigens when you have an open wound, does not mean it is the same thing as injecting antigens, and their accompanying additives.
With regard to the polio vaccine, the OPV also offered a superior immune response to the IPV. Yes, a higher incidence of paralysis associated with the OPV, but also gut immunity (preventing transmission), which is not as developed with the IPV.