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Something is up with my liver. Not exactly sure what but pretty sure why or at least part of the why. Here is the story condensed for easy reading, I hope

Back in Dec. I went to the Dr about another issue and she decided to run blood tests on me since it had been a very long time since I had the whole work up.

The bw came back showing extremely high cholesterol and triglycerides so the Dr. insisted I start a statin med. Vytorin was the brand. I have always been very leery of statins main reason being no one in my family has been able to take them without major side effects. I explained this to the Dr. and she felt that my risk of not taking it was higher than the risk of taking it.

My liver enzymes at the time where already off. The Dr. felt this was due to fatty liver (though my new NP dosnt think I am overweight enough for that). So I reluctantly agreed to try the statin because the risk was very real with my chol. and tri. so high.

Well within 2 weeks my muscles started to hurt by the end of the 4th week I took myself off the med because I couldnt even load the dishwasher without extreme pain.

Went in for bw and the results showed that my body was indeed reacting very poorly to the vytorin. Big surprise there Not only was my liver upset but my creatine Kinase levels where really off.

I had repeat bw done which showed that things where getting worse not better. So the Dr.decided to send me to a rhumatologist she checked me for all sorts of stuff and nothing really showed up except the fact that I have rather large red blood cells

Anyway I am going to put up the enzyme levels and the creatine levels from all the bw so you can see how things look and I hope that someone will know something about it and point me in the right direction to research.

BTW I have 5'7, 38 yo and weigh 198 I go on the 21st for a liver u/s because my numbers are still way off actually the worst they have been since this all started.

12/07/09 before starting the Vytorin
AST (SGOT) 49 Normal level (4-34)
ALT (SGPT) 70 Normal level (0-55)

1/21/10 After having been on the Vytorin for just shy of a month
AST (SGOT) 53
ALT (SGPT) 85
Creatine Kinase 146


1/26/10
AST (SGOT) 47
ALT (SGPT) 84
Creatine Kinase 153


2/08/10
AST (SGOT) 38
ALT (SGPT) 58
Creatine Kinase 253

2/10/10 (Dr. decided to add some more tests here)
AST (SGOT) 47
ALT (SGPT) 65
Creatine Kinase 229
Aldolase 9.1


4/15/10 (Results from the Rhumatologist bw)
AST (SGOT) 61
ALT (SGPT) 85
Creatine Kinase 250
Aldolase 9.8


7/8/10 (last set of bw)
AST (SGOT) 70
ALT (SGPT) 90
Creatine Kinase 178


As you can see my poor body isnt going back to normal very fast at all actually some of the numbers are even worse. With the liver enzymes being nearly double what they should be.

The NP wants me to start a non statin, Trilipix but from what I am reading online it to could affect my liver and possibly muscles so I havnt started it yet and dont intend to until I get the results of the liver u/s and maybe not then.

I have googled a bit but so far havnt come up with much. So if you have any thoughts I would love to hear them