Can the Factor V Leiden & PT20210 be tested while pregnant?

[kalamos23]

I was scheduled to get tested for the full recurrent loss pane as soon as I got back from vacation. I miscarried 7/12 and they were going to have me wait 6 weeks to make sure my blood levels were prepregnancy normal (with regards to anti-immune stuff in the blood, not the HCG). Well, we're pregnant again, and I really need to know if I have Factor V or Prothrombin or if we are dealing with an immunological issue. Obviously we can't test for the immunological issues while pregnant as the results would be skewed, but I'm already preauthed by insurance for the Factor V and Prothrombin tests.

Since these are genetic tests and therefore not affected by pregnancy, they should be fine to test while pregnant, correct? My OB is saying that we can't because I'm pregnant and it changes the blood (which to an extent she is right due to acquired activated protein C resistance - BUT that just means they should skip right to the genetic testing and skip the screening test as the screening test will be possibly falsely positive).

Anyone have any links to medical journals or papers that show this?

[teeg1973]

Sorry I don't know of any articles that pertain to your exact question, but my understanding of several of the blood clotting disorders is similar to what you have stated....I would guess that any of the genetic issues the predispose ones to clotting could be assessed regardless of pregnancy status.

I browse another bulletin board/site that has a group of ladies who are all heparin/lmwh's for their pregnancy....most due to identified blood clotting disorders or history of dvt's/pe's. While it is a very mainstream site, this particular BB has been very informative for me. Your question might have a larger audience over there if you feel up to it...

Best of luck,
Tracy