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Bovine polyomavirus in vaccines - any knowledge?

post #1 of 4
Thread Starter 
I remember reading a thread about bovine polyoma virus in vaccines in archives but now cannot find it. I am very keen to now start vaccinating my children. but have read on pubmed that up to 66% of all bovine serum used to make vaccines tests positive for bovine polyoma virus. I cannot though find much information on whether this virus in removed by the time the serum finds its way into vaccines. I remember one poster talking about it being inactivated by the time it reaches vacccines, but I am not sure if this is correct, and presumably might only work for vaccines which are not live viruses. Anyone in the know about this? Seems to be only a recently discovered thing.
post #2 of 4
Thread Starter 
anyone? Or anyone have an idea where the other thread is?
post #3 of 4
I don't know if BSE (mad cow) is related to polyomavirus but these articles involve the US FDA but are UK:

http://www.guardian.co.uk/uk/2000/oct/22/foodanddrink

http://www.guardian.co.uk/uk/2000/oct/21/nhs.bse

As far as the substrates of any vaccine being purified, they are supposed to be clean of residual cellular matter however it seems that there are still cells and sometimes they can be contaminated too. People with severe egg allergies are at risk of the flu vaccine as it is grown on egg protein cells. Vaccine substrates can also contain animal diseases of which they are meant to be purified from, but that is not the case with the polio vaccine in UK and the porcine virus of the Rotavirus vaccine here in the US but I don't know if they are active or zoonotic:
http://www.virology.ws/2010/03/29/de...-contaminants/
post #4 of 4
Thread Starter 
Thanks for replying Asiago. Bovine polyomavirus is not related to cjd. It is related to SV40 in the sense that both are polyomaviruses.
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