I have info to support giving babies with prolonged jaundice vitamin K.
If that is what you are looking for, the info on vitamin k as a cause of jaundice came from the days when they would routinely supplement newborns with 45 milligrams a day, which is no longer done and hasn't been done since the 1960's.
Here is a link to a 1994 full Tex article that talks about treating prolonged jaundice with vit K
http://www.ncbi.nlm.nih.gov/pmc/arti...8/?tool=pubmed
Then in more recent years prolonged jaundice becomes one of the vitamin K deficiency Bleeds prodromal symptoms along with bruising and intestinal bleeds and blood seeping from umbilicus.it is in the 1999 paper compiled by a committee defining vitamin K deficiency bleeds.
Thromb Haemost. 1999 Mar;81(3):456-61.
Vitamin K deficiency bleeding (VKDB) in infancy. ISTH Pediatric/Perinatal Subcommittee. International Society on Thrombosis and Haemostasis.
Sutor AH, von Kries R, Cornelissen EA, McNinch AW, Andrew M.
Universitäts-Kinderklinik, Freiburg, Germany.
sutor@kkl200.ukl.uni.freiburg.de
" DIAGNOSIS: In a bleeding infant a prolonged PT together with a normal fibrinogen level and platelet count is almost diagnostic of VKDB; rapid correction of the PT and/or cessation of bleeding after VK administration are confirmative. WARNING SIGNS: The incidence of intracranial VKDB can be reduced by early recognition of the signs of predisposing conditions (prolonged jaundice, failure to thrive) and by prompt investigation of "warning bleeds"."
And here is a quote from a recent study done
Arch Dis Child Fetal Neonatal Ed. 2009 Nov;94(6):F456-60. Epub 2009 May 3.
Vitamin K deficiency bleeding in cholestatic infants with alpha-1-antitrypsin deficiency.
van Hasselt PM, Kok K, Vorselaars AD, van Vlerken L, Nieuwenhuys E, de Koning TJ, de Vries RA, Houwen RH.
Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584EA Utrecht, The Netherlands.
p.vanhasselt@umcutrecht.nl
CONCLUSIONS: The risk of VKD bleeding in breastfed infants with A1AD was high and did not correlate with serum level of conjugated bilirubin at diagnosis. A similar absolute risk was previously reported in breastfed infants with biliary atresia under the same prophylactic regimen. This confirms that-without adequate prophylaxis-the risk of VKD bleeding is uniformly high in exclusively breastfed infants with cholestatic jaundice, irrespective of underlying aetiology.
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