Under 2s have been an area where flu vaccination study has shown little benefits but also it has been an area where study has been lacking-- and the ones we do have have many faults. The lancet has designed a study to address this issue:
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Quote:
We enrolled 631 children into our study with a mean age of 2·13 years (range 9—40 months). Seven (5%) of 154 fully vaccinated children and 61 (13%) of 456 unvaccinated children contracted influenza during the study (effectiveness 66%, 95% CI 29—84; p=0·003). In the subgroup of children younger than 2 years, four (4%) of 96 fully vaccinated children and 21 (12%) of 172 unvaccinated children contracted influenza (66%, 9—88, p=0·03). We were unable to record any adverse events associated with the vaccination of the children in our study.
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http://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2810%2970255-3/abstract
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And, if you can get the full text, you will see that the flu vaccine failures were almost entirely in kids who got a B strain that was not covered by the vaccine.
