I have tried to do online research about this and I have ended up really confused, so I am hoping there is someone here who has the skinny and can help me out. So, I have read in many reliable sources that the PKU part of the newborn metabolic screen is not that accurate until a baby has been drinking breast milk (not colostrum) for at least 24 hours. But I have also read that it is better to catch the other disorders the test screens for as early as possible. Does that mean there is no way to avoid having my baby put through that torture twice? I initially decided to decline the test in the hospital, as it's unlikely we'll be there when my milk first comes in, much less 24 hours after that, and have it done at the first ped visit, which would probably be about 2 days after leaving the hospital. Is that too late for detecting the other disorders? FWIW, with my first two the test was done "too early" for it to be accurate w/r/t PKU, but we were NOT asked to do it a second time. Still, it doesn't seem to make sense to do it this way (24 hrs after birth with my first, 48 for my second) for breastfed babies. Yet I rarely hear anyone question it. Is this because PKU is so rare that the chance of a breastfed baby slipping through the cracks is infinitesmally small?