I wanted to share my story – knowing, of course, that it’s not necessarily anyone else's story and knowing mine’s far from complete as I write this. But I’m pretty awed at the events of the last few months and the power of getting the right support! I just received a positive pregnancy test on July 31, 2011 – I’m five weeks tomorrow – my hcg’s are really strong. I’m shocked and thrilled.
My fertility history:
- Aug. 09 - Pregnant second month we tried – ends in chemical pregnancy
- Sept. 09 --Pregnant again – Learned at 10 week apt. that embryo died at 7.3 weeks (took until 12 weeks to miscarry)
- take six months off of trying to heal ( I got off ALL my supplements)
- get back on supplements and begin trying in June of 2010
- by March of this year we see RE for fertility testing – All tests normal.
- IUI during the clomid challenge test – negative
- we decide we don’t want to do further fertility treatments, at this time and decide to take the summer to “be” with each other and see what happens.
- In May of this year my ND requests that my RE do a recurrent miscarriage blood panel. (SO much blood : )
- All tests come back normal except for my MTHFR gene – I have two copies (mutations) for A1298C, which is related to Folic Acid resistance.
My RE’s office says that he falls into the camp of believing that this has "no connection to your miscarriages” and tells me to “increase my dose to 1 mg of Folic Acid a day, because it "can’t hurt anything”
I called my ND’s office that day and at that apt. I learned much, much more:
This gene is important in the metabolism of homocysteine, an important amino acid. Having two variants/mutations in the MTHFR gene, such as A1298C, can cause elevated homocysteine levels. Elevated homocysteine levels have been implicated in many health issues including pregnancy loss and other pregnancy-related complications, as well as restless leg syndrome (the list goes on). My current test results showed normal homocysteine levels.
My ND recommended that I begin 1 mg of Methyltetrahydrofolate --- HUGE distinction from the folate found in prenatal supplements or OTC folate that my RE had recommended. This is folate that is already converted – taking over the role that my mutations have been preventing. In combo with the folate you need to take a B vitamin complex. She put me on B 12 complex. The series of B vitamins work together for best absorption/results. Her theory was that my body in 2009 had some folate reserves enough to get pregnant but not enough to sustain the pregnancy. Get my reserves back up and see what happens. That was May 12 of this year. I got my positive pregnancy results on July 31, 2011!!
Another change I made back in November of 2010 was to go off gluten entirely (my father and sister have Celiac and I noticed my own sensitivity to wheat and gluten). I continue to stay off gluten, and I’ve increased my intake of the MTHF folate and B-12 to two a day since I got pregnant.
I think the biggest thing I want to share with this community is to keep seeking support, however you need it. I’ve been seeing a lot of people who have wonderful intentions for helping us reach our goal of my goal of having a baby. I don’t fault my RE, but I believe I’d still be trying if I didn’t have my ND in my corner, with her interest and understanding of this issue.
Best to all,