The reason for doing an amnio is that I carry Muscular Dystrophy. I have a 1 in 4 chance of passing it on to any child I have. Girls can carry (and are largely if not entirely unaffected by that) but boys can have the disease. It's a degenerative muscle disease. I carry one of the mildest forms, but it would still leave an affected child wheelchair bound by the age of 30 and also can affect large muscle organs (like the heart- my dad had a heart transplant at 35, and my cousin with it died at 32 of heart failure).
I'm considering not doing the amnio and just testing the baby, if it's a boy, whenever he's born. From what I understand it's just a blood test, but I need to double check that. If it's invasive, then (IMO) the amnio is better. My entire extended family and DH's entire extended family really really really want us to the amnio. We wouldn't abort (god no!) if the baby has MD, so it's just to "know." But I figure if I know during the pregnancy I'll be a mess, and if I find out after the baby is born at least I'll have that connection to the baby, more so than I would at 15 weeks of pregnancy, to help soften the blow a bit. But I really just can't decide on anything. DH wants me to do it. I'm undecided. I WOULD feel better if we got testing back saying the baby does NOT have MD, but what if it's positive? Ugh, I don't want to even think about it.
We did it with our other 2 kids. It was easy, comfortable, with no negative side effects at all for me. Not even any cramping after, which is pretty good. They're both fine.
SoSurrel- the miscarriage risks are actually lower than that. They've been doing further research and testing, and now the needles are slimmer, it takes less time, the doctors who do it (here, at least, I don't know how it is the states or even other Canadian provinces) do pretty much ONLY the amniocentsis, so they have tons of experience. I was told by my genetic counsellor that the risks of miscarriage are closer to 1 in 1600, and further research on my part turned up the same information. It was a big study group, too, I think 3400 women? I am a researcher when it comes to all things pregnancy/birth/baby, and there is no way I'd subject my kid to 1 in 400 chance of death just to find out about a genetic condition that won't effect the pregnancy or how I'd feel about the baby. Although... put that way... why am I even going for it with a 1 in 1600 chance of death? Bah. Now I don't want to do it again.
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