Once Jude passed i started using it orally and vaginally immediately. I had originally planned to start with it orally at 36 weeks then vaginally at 38 weeks. At 34.5 weeks, when he passed, we knew that my cervix would need time to soften but we also knew that we needed to try for a delivery within 2 weeks if possible. I started out with 2 orally and 2 vaginally (500 mg) then in a few days I upped the dosage to 3 orally and 4 vaginally. By the second week I started to lose some plug each morning. I credit that stuff for getting my cervix ready b/c it was so early in the pregnancy for labor and if I had not used it it could have been another 2 weeks before spontaneous labor would have started. I will use it again if I ever have another baby. My first born was a failed induction b/c they induced contractions with an unripe cervix due to ROM at 40 weeks. They even knew my cervix was not ripe b/c it still felt ridged.
This time my labor was so fast and rather easy. My cervix responded to each contraction beautifully. I'm sure that results differ for different people but I had a very wonderful labor and I think the EPO is what prepared my body to respond so well.
PS. I never reached significant dilation during my first labor before the c/s, even 36 hours after ROM, so I don't think that the easier dilation had anything to do with it being my second labor. During my first labor, I never had a single contraction with pressure on my cervix, just a lot of uterus tightening but I felt NOTHING happening in my cervix. This time I could feel
the cervix blooming.