Originally Posted by Rrrrrachel
Right. And that reticle is seven years old. So maybe other studies have been done since then.
Such as this one: http://www.ncbi.nlm.nih.gov/pubmed/21272845 from 201 which concludes that giving women Tdap in ppregnancy does protect newborns. I wish I could see the full paper and methodology rather than just the abstract.
A quick pub med search turned up two other related studies. One looked at women who got the Tdap between pregnancies, comparing the newborn titers of the first pregnancy to that of the second and finding that the babies born after the Tdap had higher titers than their older sibling had had. Another one looking at newborn levels for women who had Tdap prior to pregnancy or early in pregnancy did not have promising results though, contrary to the other studies. It found that babies from mothers who had Tdap prior to prengnancy or early in pregnancy were not born with protective amounts of antibodies. This one suggested that giving Tdap late in pregnancy could be a solution, but it doesn't appear from the abstract that the study actually looked at that, so apparently just a suggestion for future study.
There were also some animal studies, one which brought up the possibility that maternal antibodies from vaccinated mice interfered with vaccinating the baby mice later. I assume they would have considered the possibility of this with humans, but I don't know what evidence they have that allowed them to dismiss these worries, or if they have been completely dismissed.
This was like five minutes of searching, so entirely possible I missed some stuff. What I did turn up is not enough to say for certain that Tdap in pregnancy will protect babies, but it is a good point in that direction. I do not have a problem giving it to pregnant women as things stand in the hopes that it will work, I just hope women are being well informed as to what the current evidence is/the lack therof, and that people are watching the numbers closely so that soon we will know for sure exactly how well it works.