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Higher dosage of Folic Acid to prevent Down Syndrome and other birth defects

post #1 of 3
Thread Starter 

I knew folic acid was important, but didn't realize that there seems to be a link in taking higher doses to prevent Down Syndrome.

 

http://www.bastyrcenter.org/content/view/635/

 

I've been taking a prenatal vitamin, but even higher doses sound like a good idea.  I'm now 3 weeks past conception.  Anyone know if high doses might still prevent DS or would it now be too late?

post #2 of 3

A higher dose of folic acid can't remove an extra chromosome (at best, it may reduce your risk of having a reproductive cell split asymmetrically in the first place), so I don't think that increased doses of folic acid during pregnancy would reduce your risk of having a child with down's. 

post #3 of 3
The article suggests that the first month of pregnancy is key, and that sufficient iron is a factor, as well. I think that all the b vitamins are incredibly important before, during and post pregnancy. I take high doses of them all. Great article!

So interesting that those chromosomal changes can occur even after conception.
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