Originally Posted by erigeron
I haven't looked at the research, but Gardasil has only been AROUND for about 5 years, so how can they really know its long-term effectiveness yet?
I think this is a good point. Is it only effective for 5 years - or has the study/existence of the vaccine only been in existance for 5 years, ergo we can say the vaccine is effective for 5 years plus, but the upper limit is unknown?
Sadly, the cancer.gov link does not answer the question.
"Gardasil and Cervarix are highly effective in preventing infection with the types of HPV they target. The vaccines have been shown to provide protection against persistent cervical HPV 16/18 infections for up to 8 years, which is the maximum time of research follow-up thus far. More will be known about the total duration of protection as research continues (7).
HPV vaccination has also been found to prevent nearly 100 percent of the precancerous cervical cell changes that would have been caused by HPV 16/18. The data so far show duration of production for up to 6.4 years with Cervarix and for up to 5 years for Gardasil—in women who were not infected with HPV at the time of vaccination (7–10)."
On one hand it says up to eight years, which is the maximum research time so far….and then in the next breath says 6.4 and 5 years. I would expect to see 8 years plus if it was a straightforward 8 years plus.
Here is a link (#7 form the above quote), published 2011
It says this:
"Immunogenicity of the bivalent vaccine against HPV-16 and HPV-18 has been demonstrated up to 8.4 years. For the quadrivalent vaccine, immunogenicity data up to 5 years show that the immune response against HPV-18 wanes after approximately 4 years. Efficacy against infection and cervical lesions associated with HPV-16/18 has been shown up to 8.4 and 5 years with the bivalent and quadrivalent vaccine, respectively. Cross-protection against non-vaccine types appears stronger with the bivalent vaccine. However, both vaccines may provide sufficient immunogenicity to confer long-term protection. Ongoing monitoring is essential."
So…I am at a loss. Is it only effective for 4-8 years, or do we only have data from 4-8 years? Time will tell.