Pregnancy and Whooping Cough Booster Questions - Page 3

[Rrrrrachel]

But that's not true. It may be that there are animal studies tht how harm to the fetus, or it may be that no data from animal studies are available. Both would qualify as class c.

[Marnica]

Originally Posted by Rrrrrachel 

But that's not true. It may be that there are animal studies tht how harm to the fetus, or it may be that no data from animal studies are available. Both would qualify as class c.

Ok well I guess I'm misinterpreting the word AND to mean including and differing significantly from the word OR meaning one or the other. 

Quote:

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

[Rrrrrachel]

From safe fetus

"Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus."

From the apa.

"Risk can not be ruled out- Adequate, well-controlled human studies are lacking, and animal studies have shown a risk to the fetus or are lacking as well.
There is a chance of fetal harm if the drug is administered during pregnancy; but the potential benefits may outweigh the potential risk."

From womenshealth.gov

"In humans, there are no good studies. In animals, pregnant animals treated with the medicine had some babies with problems. However, sometimes the medicine may still help the human mothers and babies more than it might harm.

Or

No animal studies have been done, and there are no good studies in pregnant women."
Edited by Rrrrrachel - 1/15/13 at 2:51pm

[Marnica]

Originally Posted by Rrrrrachel 

From safe fetus

"Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus."

From the apa.

"Risk can not be ruled out- Adequate, well-controlled human studies are lacking, and animal studies have shown a risk to the fetus or are lacking as well.
There is a chance of fetal harm if the drug is administered during pregnancy; but the potential benefits may outweigh the potential risk."

From womenshealth.gov

"In humans, there are no good studies. In animals, pregnant animals treated with the medicine had some babies with problems. However, sometimes the medicine may still help the human mothers and babies more than it might harm.

Or

No animal studies have been done, and there are no good studies in pregnant women."

 

Interesting how different sites have slightly different write ups. The nuances make it read differently to me. 

[erigeron]

I think of cat C as a catchall for "we don't have a clue, really". That said, there may be smaller studies on some Cat C drugs that haven't made their way to the point of changing the official recommendations. When I was pregnant I had a terrible cough at one point and researched dextromethorphan (also cat C) enough to find a fairly sizeable study showing no problems (I was in the second trimester, so I can't recollect what it said about the first trimester), so I felt okay about taking it. 

They are eventually going to revise the pregnancy categories to be more descriptive. 

[nia82]

That's why I would only agree to a category C medication if absolutely necessary and not without further research first. Unfortunately, professionals don't know much about it - I always had to look it up myself, especially later on during lactation. I was told a gazillion times by obgyns to wean as there is nothing safe to take while breastfeeding (during mastitis and kidney infection....). When I had hyperemesis I wanted Zofran but they said nope and prescribed me promethazine. I explained how I wasn't comfy with it as I am breastfeeding. Nada. So I just rode it out being sick as a dog for 32 weeks.

[Rrrrrachel]

Omg yes, the only thing worse than trying to figure out what's safe during pregnancy is trying to figure out what's safe during lactation!!

[Marnica]

Originally Posted by Rrrrrachel 

Omg yes, the only thing worse than trying to figure out what's safe during pregnancy is trying to figure out what's safe during lactation!!

Agreed. I find Hale's book very helpful in trying to figure out what's ok to take. Here is a resource for those seeking info on meds in both pregnancy and lactation. 

http://www.infantrisk.com/