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Mothering › Groups › March 2014 Due Date Club › Discussions › Harmony21 and Afp4 conflicting results... thoughts?

Harmony21 and Afp4 conflicting results... thoughts?

post #1 of 4
Thread Starter 

~~I'm confused... 28 years old, first time pregnant, and no family history issues. I had the Harmony21 early on and it came back 1/10,000 for T21/Down Syndrome, then 2 weeks ago had the Quad4 AFP4 and it came back positive 1/181 chance for down syndrome. Conflicted. Has anyone had results like this?

post #2 of 4

I haven't, but I know this is a scary time (((hugs)))

post #3 of 4

I bet your midwife/ob would know more about it :) I didn't take the tests, no idea.

post #4 of 4
Harmony is much more accurate than the quad screen. The old screenings have lots of false positives, but Harmony has 99.3 detection (or close to that) and a minuscule number of false positives (and negatives). I don't think you have anything to worry about if you got the all clear from Harmony. You should talk to a genetic counselor to get the exact information.
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Mothering › Groups › March 2014 Due Date Club › Discussions › Harmony21 and Afp4 conflicting results... thoughts?