Yes! I went throught 2 yrs of infertility, and 2 m/c's, before I tried clomid (my RE was reluctant to let me try it until she had done ALL testing, I still believe she wanted to milk me for as much testing as possible, I had one m/c under her care... we moved out of state and I saw an ob who agreed to let me try it). It worked on the first try on the lowest dose, with a combo of progesterone suppositories too (I had a luteal phase defect, the prog was taken before I found out I was pg, which is why I felt it was effective). I had a lot of spotting for up until about the middle of the second tri, and just limited my activity during the pregnancy. I had a healthy baby boy who is now 14 mo old and the joy of my life. Ironically, I am pg with baby #2, got pg this time w/o any help AND I was BFing. I heard it's not uncommon for a lot of women who have trouble conceiving baby #1 and need meds/intervention who end up getting pg with subsequent children later on. GL ttc!