I've done it, most recently on a semi-involuntary basis. I had to move, and my deadline got moved up (long story, my mother was dying), and everything was out of control for the month leading up to my move. I started out freecycling a lot of stuff, selling (or trying to sell) some stuff, being pretty organized, then packing away the stuff I wanted to keep for the movers. My father was paying for the movers, and I had a certain budget, a certain number of boxes and pieces of furniture. Anyway, I started going over my limit, weeded out stuff, repacked, packed other stuff in suitcases to take with me on the plane...then I just ran out of time. I left the apartment in a mess (wasn't going to get my deposit back anyway, still it bothers me), and left behind so much stuff I'd wanted to keep. All my artwork for my walls. My Ergo carrier. An expensive winter coat. One of those silly kid's foam rubber couches that my son loved. Et cetera.
All the while this was going on, I had been trying to get in touch with the friend who was storing my books for me. I wanted to go through them and choose a couple of boxes to keep, and he would have kept the rest. For months I tried to contact him, and he didn't have an answering machine, was never at home when I stopped by or called. I even mailed him a letter. I was afraid he'd died, and his kids hadn't thought to contact me. Then, two days before I was to leave, he called me, and apologized for not getting back to me. By that time, there was no way I could go through the books, and arrange to have them shipped.
I've done other purges over the years, but that was the most radical one I've ever done. It was pretty painful, and I still mourn some of that stuff, particularly the books. But I must say, it's really nice not to have to deal with all that clutter. That stuff really weighed me down, especially the books. I'd purged those books so many times over the years, and I swear they were multiplying themselves. I've solemnly vowed never to let that stuff accumulate again. As a matter of fact, I should probably do a mini-purge soon. My home is so much easier to clean, it's so much more manageable without so much stuff.
Oh, you know what show I love? It's called "Neat," with Helen Buttigeg (sp?). That show rocks, the woman is like a therapist. They really get into the reasons these people are hoarding stuff, and she's really sensitive, yet absolutely merciless.