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What causes autism? - Page 2

post #21 of 306
Quote:
Originally Posted by LongIsland
Sure, keep me up so I'm really a zombie when I wake up!

This is the list of tests this DAN doc performs:

*Complete blood count w/ differential and platelet count
*Serum metabolic assay (complete)
*Thyroid profile (T3, T4 and TSH)
*Amino acid profile (plasma)
*Organic acid profile (urine)
*Ammonia level
*Lactic acid level
*Pyruvic acid level (pyruvate)
*Heavy metal profile (lead, mercury, arsenic and cadmium), blood
*Vitamin A level
*Zinc and copper (serum)
*Measles, mumps and rubella antibody IGG titers
*Fragile X
*IgG, A, M, E
*IGG subclasses
*T cell function tests
*Myelin basic protein and neural axon filament antibodies

Okay, if you want to, stick them up.

I'm disappointed they don't do dysbiosis and the other though. And WHY do they not do the other minerals????

Where are the liver function tests?They are often abnormal if there is a vitamin A issue...
post #22 of 306
Thread Starter 
So where, if anywhere, do you all think the demyelination issues come into play?
post #23 of 306
Quote:
Originally Posted by Momtezuma Tuatara
I'm disappointed they don't do dysbiosis and the other though. And WHY do they not do the other minerals????

Where are the liver function tests?They are often abnormal if there is a vitamin A issue...
This testing was conducted when my son was three and I am sure the doc has to be testing more extensively now. Between then and now, this immunologist had begun to test his patients for a genetic variant in an enzyme - methylenetetrahyrofolate reductase (MTHFR). Now, with recent research conducted, I'm sure he also tests for glutathione, among other variables. A lot has happened in five years in terms of his research and I'm sure the current DAN protocol reflects this - at least I hope it does.

In any case, I can't find the results! I've looked everywhere - I hope they weren't misplaced/inadvertently thrown out when we moved three years ago or they could just merely be misfiled. I'm going to have to call the office and get copies sent. I'm glad this thread came up b/c I never would have realized they weren't in my health files!
post #24 of 306
Here is my belief.
We do not know for sure what causes Autism.
I believe the MMR can be a factor in cause in some individuals.
From my own experience I know 2 people with Autistic children and 1 with a child on the spectrum. The first 2 (one with twin boys who are both autistic) will tell you their children were like that from birth. The differences between their autistic children and their others is that noticeable to them. They both vaccinated. The 3rd person I know whose child is on the Autistic Spectrum has never been vaccinated.
post #25 of 306
I wanted to go into more detail regarding the elevated copper/deficient zinc denominator in autistic individuals as well. My son's copper/zinc ratios were significantly out of whack, so to speak. Of every mother I've spoken to (IRL and on message boards) who has had their child's levels tested - same thing.

***************************
METALLOTHIONINE PROTEIN DYSFUNCTION
Diseases that occur because of MT protein dysfunction include:
· Psoriasis and eczema
· ADD and ADHD
· Autism
· Schizophrenia and Obsessive Compulsive disorder
· Anorexia
· Alcoholism
· Chronic fatigue syndrome
· Alzheimer's

Metallothionein protein disorder, or MT is thought to have it’s root cause in an underlying genetic defect involving more than one gene. The genes have not been located in humans as of this publication. This disorder results in a decreased ability of the MT protein to function normally.

Metallothionein protein plays an important role in regulation of zinc and copper levels in the blood. They also act in the body to clathirate heavy metals as they enter the body, they help development and continued functioning of the immune system, development and pruning of brain cells, (neurons), prevention of yeast overgrowth in the intestines, production of enzymes that break down casein and gluten, production of hydrochloric acid by stomach cells, taste and texture discrimination by the tongue, behavior control and development of memory and social skills.

In February of 2000, William Walsh, Ph.D. of the Pfeiffer Treatment Center, discovered that most autistic clients exhibit MT dysfunction and that the classic signs of autism can be explained by a MT dysfunction. There are four primary types of MT proteins, each with an important role in the body.

MT-I and II are present in all cells throughout the body. They regulate copper and zinc, are involved in cell transcription, detoxify heavy metals, play a role in the immune function, and are involved in a variety of G.I. tract functions

MT-III is found primarily in the brain and functions as a gross inhibitory factor in the brain. MT-III is located primarily in the central nervous system with small amounts present in the pancreas and intestines. It plays a major role in the development, organization and programmed death of brain cells.

MT-IV is found in the skin and upper G.I. tract. They help regulate stomach acid pH, taste and texture discrimination of the tongue and help protect against sunburn and other skin traumas.

MT protein dysfunction has far-reaching implications for many diseases including Alzheimer's, eating disorders encountered in premature infants and a host of psychiatric disorders.
post #26 of 306
Thread Starter 
Quote:
Originally Posted by kewb
Here is my belief.
We do not know for sure what causes Autism.
I believe the MMR can be a factor in cause in some individuals.
From my own experience I know 2 people with Autistic children and 1 with a child on the spectrum. The first 2 (one with twin boys who are both autistic) will tell you their children were like that from birth. The differences between their autistic children and their others is that noticeable to them. They both vaccinated. The 3rd person I know whose child is on the Autistic Spectrum has never been vaccinated.
I think there is at least one "type" of autism that is probably genetic...and not just a genetic disorder, but more like a syndrome.
I think it's a totally different thing from "triggered" or "regressive" autism.
post #27 of 306
Quote:
Originally Posted by mamakay
So where, if anywhere, do you all think the demyelination issues come into play?
Here's some information which may interest you (link below):

****************
2. Recent Theories for the Pathophysiology of Autism:
Brain autoimmunity
Deficits in sulfur metobolism
Abnormal liver detoxification
Gastrointestinal abnormalities

a) Neuro-Immunopathogenesis in Autism

i. In Dr Singh’s theory, environmental factors including viruses, toxins and heavy metals may initiate immune dysfunction among genetically vulnerable individuals.

ii. Resultant changes in immune function lead to production of brain antibodies (i.e., the brain develops a pathological autoimmune response to its own brain tissue).

iii. The pathological autoimmune response to brain tissue leads to a spectrum of neuro-immune development disorders.

iv.This theory is supported by Singh’s research that found antibodies to myelin basic protein (MBP) in autistic children but not in non-autistic children including children with other disorders (such as Down's). Almost all autistic children with such MBP antibodies also had positive measles antibodies.

v. Myelination is primarily a postnatal event in the developing brain. As autism is a neurodevelopmental disorder, autoimmunity to myelin may be casually related to autism

vi. In autism, atypical measles infection, in the absence of a rash, but with neurologcal symptoms, may be causally linked to brain autoimmunity.

Singh, VJ. New Foundation of Biology, p 447-458. Berczi I and RM Gorczynski, eds. Elsevier Science, 2001). University of Utah.

This is an excellent summary (which includes more opiad information in relation to the gluten free/casien free diet, digestive enzymes, etc.):
http://www.ont-autism.uoguelph.ca/jo...ism-jun02.html
post #28 of 306
I would agree with most of that LI, which leads back to the questions I asked. If you fling life back to the nineteen thirties, and occasionally in the 1800's you would have found the occasional person on an autism spectrum disorder.

To me, autism is a very broad issue, but the foundations for potential for it have always been there. We like to think that the world is a "better" place these days, but if you read "Our Stolen Future" and other books of this kind, its patently obvious that it isn't.

To me, Autism spectrum disorders are the end point of a world in which genetics, nutrition, environemental toxins and the combined impact on the immune system all come to a triangular point of the pyramid, with the crud at the bottom and the child at the top.

In some children they don't need vaccines, because the damage in their parents is such that the child was born at the top of, or near the top of the pyramid to begin with.

Other children are so close to the top that all they need mercury from the mother's amalgams, or diet, a major mineral imbalance, which is always the result of being on the pill prior to pregancy, so that's another issue (which no-one here has talked about ~ the pill is undermining health and broadening the base of the pyramid) and/or an infection either in utero, or in early childhood,~~~ because undermining the mother's hormonal balance, will change her minerals, alter her immune system and her gut, and start to tear rents in the developing baby's whole biochemistry.

Some children only need a DPT to tip over. And one "perfect" little girl that I know, who was "perfect" (and fully vaccinated) until the age of five, was fine until she got her first MMR at 5, got mumps encephalopathy from the vaccine, and now everything has disintegrated. So when the experts talk about some "normal" age, I roll my eyes. I know a 12 year old, who was normal until the MMR booster, so there is no acceptable age at which "damage" cannot occur.

The straw that breaks the camel's back in the past have been different things. The reason we are seeing so many after vaccines in my opinion, is that never has there been a time in history when so much pressure has been put on the immune system at such a young age.

In the past, when I was a child, my first vaccine was at the age of three. My husbands first was at the age of 19. In those days, and immune system had a chance to settle itself in, and work out how the rules go. And there was far less chemical crud around, and the minerals and vitamins in food was far better than it is now. Junk food was simply non-existent. Yesterday's paper had an article in it about eating McDonalds regularly, doubles the risk of asthma etc. Well, hello? I could have told them that!

The world is teetering on a nutritional knife edge, an immunological and ecological knife edge, and immunologists and the Offits of this world, walk around with their heads up their arses. As well as being grossly underimmunised themselves.

I would so love to line them all up and update their vaccine charts with all the missing childhood vaccines, and the ones that the soldiers get as well. And since Offit considers that 1,000 vaccines in a day is fine, I'll love to put him at the front of the line.

This quote is relevant:

Quote:
“I would challenge any colleague, clinician or research scientist to claim that we have a basic understanding of the human newborn immune system. It is well established in studies in animal models that the newborn immune system is very distinct from the adolescent or adult. In fact, the immune system of newborns in animal models can easily be perturbed to ensure that it cannot respond properly later in life.”
This testimony was given verbally to the United States Senate on May 12, 1999 by Dr Bonnie Dunbar, Professor of Immunobiology with specialist work in vaccine development and autoimmunity for over 25 years, the past 17 at Baylor College of Medicine in Houston. Dr Baylor was asking the Senate for a moratorium on the Hepatitis B vaccine, which she maintains is extremely dangerous, and which carries serious debilitating side effects denied by the establishment.

But the crux of her message is to me, the key. The children who go into immediate regressive autism after vaccines are the ones who, if they had had time to mature that immature immune system may have been able to cope.

The others were just too close to the top of the pyramid either at birth, or even before.

But in a sense, "autism" is in the hands of parents.

No, we can't literally turn the clock back. But if we study hard enough, and understand the impact that food, the environment and vaccines have on the immune system, and try to avoid the known traps that may await future children, then we may be able to do something about it.

However, I believe there will still be a large subsection of Autistic children whose regression is triggered by mercury of any kind, be it from mother's amalgam, diet, or vaccines. APO-E3 appears to be the gene to look for, in that regard, because the people who get sick from amalgam in their OWN mouths are most likely to have this weakness. Not APO-E4, as Dan Olmsted mentioned. I don't know where APO-E4 fits in, as I've not researched it, because I didn't know it was relevant.


As for the rest, if parents continue to insist that their babies are pincushions from the first day out of utero, I believe we will see a huge increase, not just in autism but in other immunological based disturbances, because you can't go on sticking things into babies and assuming that nothing else will give.
post #29 of 306
What a HUGE question!

I think I'll just : on this one and learn from others.

Edited to add: Great discussion. There's so much "detective" work and details to piece together to understand the big picture. Kudos to MT, LI and mamakay for having the patience to do a lot of the legwork.
post #30 of 306
this is very interesting. My ds has gut problems [ bleeding in the gut from 3 months old, now finally under control] and we were advised by a specialist to keep his diet free from gluten and dairy until he is at least two to avoid development issues. he is, THANK GOD, doing fine, i think. He is unvaxed. But i had my breast milk tested for toxins when his gut started bleeding, i couldn't understand, they said it was a food allergy, and he was solely breastfed, they said it must be food proteins in my milk so i tried lots of eliminations. I found my breast milk had an higher than average quantity of lindane, a particularly nasty pesticide, which was really alarming. I have had it tested again recently, and the levels have dropped to below average. apparently lindane levels do decline in breast milk. I would like to know, how do i get rid of these chemicals in my body? I eat organic, maybe on ly for the last three years, and i stay away from all chemicals and pesticides. I don't want another baby of mine to go thru this, if we have one. Any advice?
post #31 of 306
buff I don't have an answer to your question but I would love to know how you got your breastmilk tested? That is really interesting! Do you know where the pesticide found in your breastmilk is used? (i.e. lawn chemicals, foods, ...)

Edited to add: okay I found some info on where lindane might be used
Quote:
Lindane is found in air, water and soil samples throughout the world. Lindane is documented in human breast milk and amniotic fluid. Many countries have banned lindane. Unfortunately, in the United States, it is still widely prescribed and used on children and their families for treating head lice and scabies. It is also used on pets, livestock, fruits and vegetables, cotton, wool, tobacco, plants, trees and as a wood preservative.
post #32 of 306
yep, i'm afraid i was given lindane by a pharmacist when i had a rash on my body. I lived in a very poor area at the time where scabies was rife and the doctor told me over the phone to use the lotion, which i did. It didn't work and i went to a dermatologist who told me it wasn;t scabies, but it was too late. I rue the day i used that stuff. Wish i could get it out of my body now and not into my baby.
post #33 of 306
BTW it was a UK lab i used, that's where i am, but you have to get a referral from a doctor or health practitioner. there must be an equivalent in the States..
post #34 of 306
Quote:
Originally Posted by buff
yep, i'm afraid i was given lindane by a pharmacist when i had a rash on my body. I lived in a very poor area at the time where scabies was rife and the doctor told me over the phone to use the lotion, which i did. It didn't work and i went to a dermatologist who told me it wasn;t scabies, but it was too late. I rue the day i used that stuff. Wish i could get it out of my body now and not into my baby.
Wow buff sorry to hear. I wonder if you should consult a naturopath or homeopath? You might be able to go on some sort of cleanse or get a remedy that will help to eliminate the toxin from your body. Are you still breastfeeding? This is a consideration as well as you don't want to cleanse out anything your baby needs or excrete excessive amounts of anything bad into your breastmilk (not sure if that can happen during a cleanse)! I'd definitely speak to a holistic professional. Even if you can't do a cleanse or take the required remedy while you are breastfeeding, you may be able to do it when you are done breastfeeding the first and before a second child.
post #35 of 306
yes, i will try when i stop breastfeeding. can't tell ytou how i cried about it, thinking about how my baby is getting this awful toxin from me. If the doctor i had rung had any sense, they would have asked me if i had had any close contact with anybody that had scabies, that is the only way you can get it, and i hadn't. If i had known not to trust doctors then i would have got another opinion, but in those day, seven years ago, i trusted them. Very angry about it - they don't think twice about it, do they? Lindane banned all over the place now.
post #36 of 306
Buff, I'm amazed. My friend whose autistic child I mention above, was also given lindane for scabies when she was breastfeeding, and then she got head lice (she was a teacher) and they used some awful toxic stuff on her for that. It wasn't until her child was 12 months that he had his first and only vaccine, and I'm sure that both the lindane, and the gunk they used for headlice is part of the renting of his immune system apart, prior to his vaccine.
post #37 of 306
oh god its scary MT. I can only hope and pray my ds will be ok - he seems to be developing normally, thank God, but this doesn't fill me with confidence.
post #38 of 306
Oh you silly uneducated hippy mamas discussing medical things like you know what you are talking about.......

I will print some of this out and so it to my father to PROVE to him that we KNOW what we are talking about , we DO our research and YES we are scaring the crap outta the industry.

You's some smart mamas...
I'm gonna grab my dictionary and come back to read.
post #39 of 306
What a fabulous discussion. My guy has horrible digestion (stool tests showing nasty bad bacteria) and a lot of sleep problems, so I've done some research in the autism community for advice b/c they've BTDT. There but for the grace of God go I.

Quote:
Originally Posted by buff
I found my breast milk had an higher than average quantity of lindane, a particularly nasty pesticide, which was really alarming. I have had it tested again recently, and the levels have dropped to below average. apparently lindane levels do decline in breast milk. I would like to know, how do i get rid of these chemicals in my body? I eat organic, maybe on ly for the last three years, and i stay away from all chemicals and pesticides. I don't want another baby of mine to go thru this, if we have one. Any advice?
I imagine it would decline when the source of it has stopped. Breastmilk is comprised of the contents of your bloodstream.

My advice is superior nutrition. And my view is based on the books, "Nourishing Traditions" and "Nutrition and Physical Degeneration".

http://www.westonaprice.org/traditio...ry_wisdom.html
http://www.mercola.com/2001/jan/21/weston_price.htm

WAPF website has enormous amount of info:
http://www.westonaprice.org/splash_2.htm

I would especially recommend homemade bone broths from organic animals and homemade yogurt/kefir or fermented veggies everyday.

The broths are an excellent source of minerals in easily absorbed electrolyte form.

The cultured food will provide you with probiotics many many times the level of capsules you can purchase in a store. They will reline your gut with friendly bacteria: nutritional and immunological gold. Culturing also increases the nutrient content of the foods.

Also, traditional sources of vitamin A and D in animal fats and livers (cod liver oil too).
post #40 of 306
Quote:
Originally Posted by LongIsland
This auto-immune response may also reduce levels of the dipeptidyl peptidase (DPP)-IV enzyme, thereby connecting vaccines to the opioid theory of autism.[/I]
LI,

Your son's symptoms went away on a GFCF diet only?

Incidentially Houston Nutraceuticals enzymes are the only ones that are reported to supply DPP-IV effectively enough for many ASD kids go off the GFCF diet with them.

www.enzymestuff.com

I worry about the backlash that will happen to the autism community when the dx numbers don't come down *enough* with thimerosal being removed from the vaccines. Mercury from vaxs is a large factor but not the only one. This explanation of causes is a lot more difficult to "sell".
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