|CONCLUSIONS: Despite efficient placental transfer, low maternal pertussis antibody levels and their rapid decay in infant sera leave infants with little humoral protection against pertussis. These data support the rationale for maternal or neonatal immunization, with acellular pertussis vaccines, to prevent life-threatening pertussis in early infancy.
They decay very fast though...
But what this ignores is this. If a mother is able to transfer antibody placentally, then she would have enough to also provide ongoing antibody in breastmilk, though there haven't been very many studies looking at this, and.. there is still debate, as to whether what they think is the antibody to pertussis is actually the antibody to pertussis.
I've only found one study that showed this:http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=2482004
Class-specific antibodies to Bordetella pertussis, Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis in human breast-milk and maternal-infant sera.
Kassim,-O-O; Raphael,-D-H; Ako-Nai,-A-K; Taiwo,-O; Torimiro,-S-E; Afolabi,-O-O
Ann-Trop-Paediatr. 1989 Dec; 9(4): 226-32
"Children under 2 years of age are most susceptible to acute respiratory infections caused by Bordetella pertussis, Haemophilus influenzae type b, Streptococcus pneumoniae and Neisseria meningitidis. We analysed milk samples and sera from mother-infant pairs for specific antibodies that may enhance protection against the bacterial pathogens. The results show that the breast-milk samples contained significant titres of specific IgG and IgA antibodies to the four organisms, although the mean IgG antibody levels were higher in maternal sera than in breast-milk. On the other hand, the mean IgA antibody levels to the four organisms were higher in breast-milk than in both maternal and infant sera. IgM antibodies to these organisms were relatively low or absent in many milk and serum samples. Nevertheless, the significant concentrations of specific IgG and IgA antibodies in milk samples may indicate a protective role for breast-milk against the four infections in early childhood."
If you click on related articles there are nine pages, but nothing much on pertussis...
There is this one here:http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=1295946
Which shows that mothers with good immunity to pertussis have pertusiss IgA in their colostrum, so you'd think it would be in their breastmilk, and they use this as justification to vaccinate pregnant women to protect babies.
And there is this one, which would back up the idea that vaccine-induced immunity only produces IgG class, whereas natural immunity because it uses cellular pathways as well as humoral pathways is the originator of the IgA antibodies:http://www.ncbi.nlm.nih.gov/entrez/q..._uids=16011994
But again, its used as a justification to vaccinate all and sundry, not to elucidate the mechanisms of immunity and protection transfer in the case of natural versus vaccine-induced.
With pertussis the two are very different.
It seems to be an area that no-one particularly wants to study.