THE Adrenal Fatigue Thread - Page 115

[Goddess3_2005]

Can someone tell me if perifiral neropathy is part of this? I have just been diagnosed with this and I have numbness in my face, neck and upper back and toung that has been undiagnosed as of yet..

[bluets]

Originally Posted by Metasequoia

How would one fix this dysfuntion?

Thank you SO much for explaining this to me.

i think you might need to do some more pinpointing to figure out the exact problem. if your CYP pathway is dysfunctional, you'll have additional problems: http://arjournals.annualreviews.org/....120501.150216

so... i'd start digging to see if there are tests to determine genetic mutations in the steroid hormone pathway that you can take to find out exactly which one (if any) you have. or see if there are tests for other metabolites downstream from androstenedione to see if there are other pathways... i'm not sure if these hydroxylases are enzymes that one can take orally.

what i did learn in this digging is that some of the chemo drugs for breast cancer therapy try to suppress the conversion of androstenedione to estrone.

should we spin off your steroid hormone pathway discussion into its own thread? or do you think this still belongs in this gigantic thread?

[Metasequoia]

Originally Posted by bluets

i think you might need to do some more pinpointing to figure out the exact problem. if your CYP pathway is dysfunctional, you'll have additional problems: http://arjournals.annualreviews.org/....120501.150216

so... i'd start digging to see if there are tests to determine genetic mutations in the steroid hormone pathway that you can take to find out exactly which one (if any) you have. or see if there are tests for other metabolites downstream from androstenedione to see if there are other pathways... i'm not sure if these hydroxylases are enzymes that one can take orally.

what i did learn in this digging is that some of the chemo drugs for breast cancer therapy try to suppress the conversion of androstenedione to estrone.

should we spin off your steroid hormone pathway discussion into its own thread? or do you think this still belongs in this gigantic thread?

I think I need to be a member of something to read that page you linked to.

I think I'm getting lost - my head is spinning.

What does that imply about the chemo drugs? That I could have somehow been exposed to this & therefore my build up of androstenedione could be because it's not converting to estrone? My mother never took chemo drugs, nor have I.

We can definitely make a spin-off thread, but I have no idea what to title it...all of this pathway talk if Greek to me.

[georgia]

Hi! I just noticed this thread has surpassed 2,000 posts, and typically, we need threads to stay under 2K posts or server can get cranky. Please feel free to start a new thread and link back to this one in the OP. Thanks so much, and sorry for the inconvenience!