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Progesterone suppositories?

post #1 of 27
Thread Starter 
I had two early miscarriages, with the doctor told me is totally normal, but if I wanted to, he could put me on progesterone after ovulation because this could be a possible issue. So I started a few days ago, and EEeewwwwww!! If I turn out to be pregnant, it seems like I"m going to have to wear a pad for 3 months. Is it really supposed to ooze out so much? I'm doing it twice a day.

What has been your experience?
post #2 of 27
Quote:
Originally Posted by ktcl View Post
I had two early miscarriages, with the doctor told me is totally normal, but if I wanted to, he could put me on progesterone after ovulation because this could be a possible issue. So I started a few days ago, and EEeewwwwww!! If I turn out to be pregnant, it seems like I"m going to have to wear a pad for 3 months. Is it really supposed to ooze out so much? I'm doing it twice a day.

What has been your experience?
Mine weren't that bad, but I was only doing them at night before I went to bed. Is it possible to do two but at night? Or only do it once a day? I was on 100 mg, and will be again next time.
post #3 of 27
My doctor offered them to me, I'm doing Clomid instead (different story).

Anyway...she said I would do them twice a day as well, and her suggestion was to set an alarm and get up one hour before you normally do, insert the progesterone, then lay back down. The other one was to be done before bed. I know that's kind of a pain, but that way it would soak in a little more maybe?
post #4 of 27
I was told to do them twice a day but like you couldn't stand the oozing. So I just did one right before bed, and wore panties to bed. But yes, I did that until week 12 (so actually more like 2 months from the BFP).
post #5 of 27
Thread Starter 
Thanks for the suggestions. I can't really imagine getting up to an alarm as DS has me awake by 6 am most days, but maybe that is the best approach. So does the high amount of oozing mean that not much is getting in? I don't reallyunderstand how suppositories work...
post #6 of 27
I had to do them 3X a day, but didn't have a problem with them oozing. I didn't use the applicators that came with them though. Sorry for tmi but I found them easier to insert by using a tampon applicator.
post #7 of 27
I've been doing this twice a day for just a few days now. What the nurse in my RE office told me is to put it as far up and waaaayyyyy back as possible. Don't just put it in like a tampon, but try and get it right up next to your cervix. I had one day where I didn't get it back far enough and I definitely noticed more discharge. Mine are like soft gels--about the size of an almond.
post #8 of 27
They are oozy when I use them too. The reason for using them twice (or even 3x) a day is that it keeps your progesterone levels at an optimal level over a 24 hour period. Doing once a day lends itself to more of a rise and fall. Although when using progesterone shots, that's only done once a day. Probably because it would be a bit barbaric to do more frequently than that.

I was told to lie down for 1/2 hour after inserting the suppository.

I have to say that given the ooze factor, there's a definite advantage to the progesterone in oil shots. However after 100+ shots over the past year, my *ss needed a break
post #9 of 27
Hated them! HATED THEM! They also gave me my first yeast infection *sigh*

I was told to do them 3x day after IVF. Had to do them at work as well as morning and evening. Bleh. They were gross and frustrating. They also gave me vertigo.

I was told that they can be taken rectally as an alternative, and that it cuts down on the ooze. Gross... but good to have alternatives I guess?
post #10 of 27
also hated them. HATED! I went through a whole package of panty liners. And no sex! stupid progesterone. Except it did it's thing, so I won't complain too loud.
post #11 of 27
hi!

My last IVF cycle the RE used a product called Crinone. I've used both PIO and the suppositories, and I have to say that Crinone is the BEST. It's a gel that comes in its own applicator. Used night and morning and it doesn't goop out during the day. Only yuk factor is sometimes the left-over gel (inactive ingredients) come out in little clumpy blobs during urination. MUCH better than a huge needle or a gloppy, messy suppository.

Hope this helps!

Leslie
post #12 of 27

Progesterone

I normally take oral progesterone. If you find the suppositories to be a problem you can request the pills. I tend to have a lot of side effects from them, but most women don't seem to have a problem. The pills can also be used as a suppository and don't seem to leak too much.

Heather
post #13 of 27
Hello,

I use them twice a day. I get up about an hour early or so to go pee and insert it then afterwards and go back to bed. I don't have any discharge. I also felt like I was not getting it up there far enough and I found while sitting on the toilet it helped. My suppositories look like Tylenol capsules.

Any of you on Progesterone suppositories did your period come late? I have not started yet and I am usually right on time. I am only 2 days late though. I just thought I would ask.

Hauoli lani
post #14 of 27
Yes, progesterone can make your period late. Unfortunately. Monitor your temp and you'll be able to catch when it drops. When I do the progesterone in oil shots it really throws my period off - I do a pregnancy test 18 days post ovulation and then stop the shots (if it's negative). It still takes 3-4 days after stopping the shots for my period to kick in.

I didn't notice my period thrown off as much with the suppositories, even though I was taking the same dosage as the PIO. Which makes me wonder how much I was loosing due to leakage.

Lisa
post #15 of 27
Hi,
I take Prometrium oral pills as suppositories. They are not too messy and they do take away my pms and cramps (amazing!) but I don't like the idea of being in control of this hormone. My OB says to test at 14dpo and if neg. stop the Prometrium at that point. LisaG--did you decide to test at 18dpo on your own or did your RE/ob recommend it? I always feel uncomfortable about stopping--what if I'm a late implater. I know that some people don't get positives until later... And it takes my period about 4 days to start after I stop the Prometrium.
post #16 of 27
Funnygrace - no my RE/ob/gyn did not give me the 18 day recommendation, that's purely my own doing. My ob/gyn who prescribed the PIO told me to keep doing it until I got my period. Maybe it would eventually come, but I got impatient waiting for it once CD 35 rolled around and I still had a negative pregnancy test.

With my 2 previous pregnancies I tested positive on CD 28/29, so I'm pretty confident I'm not a late implanter. Also, with both pregnancies I had a strong sense that I was pregnant - things felt very different than pre-period.

That said, your miles may vary and by all means do what seems best for you. There are always women pleasantly surprised by a late implantation positive pregnancy test.
post #17 of 27
Thanks, LisaG! This month I'm not taking progesterone, so I've got some time to not think about it and mull it over subconsciously before starting up again next month. Very long cycles does not seem fun...
post #18 of 27
I used the prometrium 100 mg, and didn't have leakage issues, but did have severe mood swings. Does anyone know if the prometrium comes in a lower dosage (ie. 50 mg capsules)? BTW, it lengthened my LP from about 7 days to 13 days....
post #19 of 27
I'm interested in a 50mg dose too. My ob said that Prometrium only comes in 100mg. But I know that you can get suppositories made at a compounding pharmacy, and I'm thinking about looking into that and seeing if they can make 50mg suppositories.
post #20 of 27
FunnyGrace, I'm going to try and cut mine in half! Remind me in a few days to let you know how that goes.
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