I use them for AF (have to try that trick for TTC though - good idea) and yes, they do take practice but I really like them now. For me, I've found that it's easiest to do everything while still seated on the toilet: lay out a piece of TP for wrapping the old cup in and pull out and open the new cup, pee, wipe that up, reach in with middle finger to loop around inside edge of cup, pull it out (but not out of the toilet because it WILL need to drip), wrap it up in the pre-prepared TP then slip that into the package of the new cup, wipe some more, squeeze new cup a few times to make it more flexible, then insert it while still on the toilet so everything is nice and relaxed. I make sure to push it towards my spine rather than straight up because it's more comfortable and finds it's position quicker, and I also make sure to slip it all the way in past my perinniel muscle. My hand will always get a bit bloody during this process, but it just washes away and I've found myself becoming rather fascinated with seeing all the variations of menstrual flow my body produces. OK, yes, that may actually qualify as being a bit weird. Every once in a great while I still find it necessary to perform the instead cup dance if things don't settle quite right - it goes right knee up, left knee up, repeat, squat, squat, hula, hula, hula, hula, repeat as necessary until things feel less wonky inside. Those are all the tips I can think of for right now. Hope some of it helps!