As far as I know, no, your wife wouldn't be able to obtain a visa with you as her sponsor (I am guessing you would be H1B and her H4). I'm not American, so no expert on US politics, but I think the Defense of Marriage Act prevents any federal government benefits (e.g. immigration) from same-sex couples. So it wouldn't matter if you were to work in MA or any other state that has gay marriage or civil unions.
There is the
Uniting American Families Act, that is being considered, which would change the current situation.
There is a small chance of both you and your wife finding an employer that would sponsor a H1B visa. You need to be highly specialized though.
There's the (rather expensive) option of going to college on a F1 visa, too.
If I were you I would look into B2 visa and see if there is a chance to use that one in combination with a H1B. But it would prevent your wife from working, since it is esentially a tourist visa.
I also researched ways for both of us to move to the US, as we are working in academics and there is a demand for folks like us, but it seems impossible under the current laws.
