I take EPO all the time - throughout my preg with DS and still take it now that I'm expecting with #2. Great source of GLA!
"Pregnancy and Fetal Development & EPO
Essential fatty acids have a unique role during pregnancy because of the rapid development of new cell growth, new tissues, and new organ systems in a developing fetus. Fetal development is associated with a high EFA requirement, and this supply is dependent on the amount and availability of EFAs from the mother.
Prostaglandins are also involved in the development and clinical expression of pre-eclampsia (the simultaneous occurrence of the clinical triad of hypertension, edema and protein in the urine at any time during the course of the pregnancy). These prostaglandins are modulators of vascular smooth muscle tone and platelet aggregation (blood platelets sticking together). Pre-eclampsia is characterized by increased vasoconstriction, frequently associated with increased platelet aggregation, reduced uteroplacental blood flow, and premature delivery. In a placebo-controlled clinical trial, a group of pregnant women receiving a combination of evening primrose oil and fish had a significantly lower incidence of edema."