If by acrylic you mean red heart super saver, yes, definitely ick. But there is SO much in the synthetic world outside of red heart super saver, and SUCH better quality! So, while I wouldn't want to knit with RHSS, I have knit with some LOVELY synthetics that are easy care- machine wash/tumble dry. Oh, and I don't mean encore or wool-ease either, cause I am not really a fan of either of those.
And at the same time, lots of people LOVE LOVE LOVE peace fleece, and I think I'd rather knit with/wear RHSS, lol. So, it's all in the eye of the beholder or rather, the stash of the knitter.