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200 mg zoloft  

post #1 of 11
4/8/08 at 2:13am
Thread Starter 
i have been on that dosage for 2 days now and i seem to be feeling more on edge than usual. is this a normal reaction after upping meds? i guess i should try and hold out and see. i have been on 150 for about 3 weeks and was doing ok but not perfect so i was told to try 200 mgs but to go back down if i started feeling bad. anyone have any experience with zoloft? it seems impossible to find the right dosage.
post #2 of 11
4/8/08 at 10:38am
Yes, I would think it is totally normal to feel on edge, since that is a normal thing to feel when you first start meds. Please call your doctor to make sure. Are you seeing a psychiatrist? A therapist? Both of these people would be great to call if you are having issues like this. You need a professional support team when changing doses.

In my non professional opinion, I would say it's normal. But I would really want you to check with your pdoc first.
post #3 of 11
4/8/08 at 11:16am
I wonder if zoloft is the best med for you, I think zoloft tends to be most effective at 100-150, around 175, my pysh said she would recommend either adding a med or trying another med.

You might want to see a specialist, since many dr don't really understand these types of meds.
post #4 of 11
4/8/08 at 12:35pm
Quote:
Originally Posted by mom0810 View Post
Yes, I would think it is totally normal to feel on edge, since that is a normal thing to feel when you first start meds. Please call your doctor to make sure. Are you seeing a psychiatrist? A therapist? Both of these people would be great to call if you are having issues like this. You need a professional support team when changing doses.

In my non professional opinion, I would say it's normal. But I would really want you to check with your pdoc first.
:

Hope you feel better soon.
post #5 of 11
4/8/08 at 1:11pm
IMH (and non-professional) O, feeling on edge is a sign that the dosage is too high for you. If you were feeling OK but not perfect at 150 and feel on edge at 200 then I would definitely try 175. 25 mg is enough of a difference to have an impact on how you feel. I take Zoloft and have for years. When we were figuring out the dosage, I went up 25 mg a week and stayed on the new dosage for at least a week and evaluated how I felt. I felt better and better until I went from 125 to 150 at which point I started feeling on edge just as you describe. So I went back down to 125 and stayed there. After taking Zoloft for about a year, I tried dropping down to 100 mg and after a couple weeks I noticed a definite increase in anxiety so I went back up to 125, which is what I take now.

In general you need to stay on a new dosage for a week when increasing and two weeks when decreasing to get your blood levels settled and then evaluate how your feel. Increases in depression and/or anxiety mean the new dosage is too low and increases in edginess, sleeplessness, and irritability mean the dosage is too high. The goal is to narrow in on the dosage where you feel the best, remembering that it is unlikely that any medication or combination of medications is going to make you feel "perfect".

As the previous posters said, you definitely want to be working with a doctor and/or therapist. Make sure your professional listens to you and has an approach you feel comfortable with. My doctor understood that I wanted to make all medication changes very very gradually and helped me do that.

It is frustrating, but it sounds to me like you are pretty close to finding a dosage where you feel good, if not perfect. Good luck!
post #6 of 11
4/8/08 at 2:41pm
If she had been on the med at that dose for a while, then yes, the thinking would be that the dose was too high. But it's normal to feel this way at the beginning of a dose change.
post #7 of 11
4/9/08 at 7:22pm
FWIW, I am titrating down from 100 mg to 50mg then 25mg and I had that "on edge" jittery feeling for three days and I couldn't sleep until last night.

My sister is a clinical neuropsychologist and she said that whenever there is a dose change up or down, your body will react. Just continue with your dosage and let your body adjust.
post #8 of 11
4/9/08 at 10:52pm
I'm on Paxil and have been through a number of dose changes up and down. In my experience, it's very common to feel on edge both up and down.

My psych is very comfortable prescribing 200 mg of Zoloft, and I know many women who've been on 250+ mg.

In my experience, the 'on edge' feeling was worst about day 3-4 of the dose change, and then got better. If it's not better after about 10 days, contact your prescribing doctor -- it could be that you can try 175 for a while and see how you do.
post #9 of 11
4/10/08 at 5:06pm
Thread Starter 
Quote:
Originally Posted by ~Mamaterra~ View Post

My sister is a clinical neuropsychologist and she said that whenever there is a dose change up or down, your body will react. Just continue with your dosage and let your body adjust.
thats what i'm doing, i'm feeling much better today too. thanks for all the advice everyone
post #10 of 11
4/10/08 at 5:40pm
Yay! So happy to hear that.
post #11 of 11
4/10/08 at 5:46pm
Quote:
Originally Posted by stephanieb View Post
thats what i'm doing, i'm feeling much better today too. thanks for all the advice everyone
That's great! Glad you're feeling better.
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