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Microcalifications on Abnormal Mammogram - Help please?  

post #1 of 3
Thread Starter 
I wanted to ask this here. I do believe some of the best breastfeeding minds are here on MDC. (I am going to cross-post this in Health & Healing and Breastfeeding Beyond Infancy. Mods, please offer guidance if I should post elsewhere. I'm just looking for thoughts, ideas, theories, etc. (I am not looking for debates on whether or not to have mammograms, or any medical treatments. Thanks.)

My sister was diagnosed with breast cancer at 38, and by the extent of it, it appeared the cancer had been present and growing for many years. I am 31, and just had my first digital mammogram to establish a baseline. To my shock (and to my dr's), it came back abnormal for BOTH breasts. My mammogram results showed many clusters and some pairs of microcalicifications bilaterally, in both breasts. It states that the micrcocalcifications in my breasts are in a "mildly nodular pattern which is stable." The report says there are also "some punctate calcifications" and "dense parenchyma." Of course, I had to start googling as soon as I read the report.

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"Microcalcifications are specks of calcium that may be found in an area of rapidly dividing cells. The residue left by rapidly dividing cells can appear as microcalcifications. When many are seen in a cluster, they may indicate a small cancer. About half the cancers detected appear as these clusters."
http://ww3.komotv.com/Global/story.asp?S=1230164

"Microcalcifications, specks of calcium found in an area of rapidly dividing cells, are the first sign of breast cancer in more than half of all cases."
http://publicaffairs.uth.tmc.edu/hle...tion-1007.html

"Macrocalcifications are bigger bits of calcium, and are not usually linked to breast cancer.
Microcalcifications are quite tiny bits of calcium, and may show up in clusters, or in patterns (like circles or lines) and are associated with extra cell activity in breast tissue."

http://breastcancer.about.com/od/mam...ifications.htm

"Microcalcifications: Microcalcifications are tiny specks of calcium in the breast. They may show up alone or in clusters. Microcalcifications seen on a mammogram are more of a cause for concern, but still usually do not mean that cancer is present. The shape and layout of microcalcifications help the radiologist judge how likely it is that cancer is present. In most cases, the presence of microcalcifications does not mean a biopsy is needed. But if the microcalcifications have a suspicious look and pattern, the radiologist may recommend a biopsy.."
http://www.cancer.org/docroot/CRI/co...ocedures_5.asp

"Calcification. With high-quality films and use of a magnifying glass, detection of microcalcification should not be a perceptive problem. Many cases of high-grade ductal carcinoma in situ (DCIS), the most common subtype found in screening practice, exhibit specific mammographic features of casting type microcalcification due to comedo necrosis (Figure 4). This type of DCIS accounts for 54% of DCIS detected in screening practice.[14] However, many cases of high-, intermediate-, or low-grade DCIS are detected on mammography as clusters of microcalcification with mammographic features indistinguishable from appearances due to benign change (Figure 5). In fact, on review of previous mammograms of newly diagnosed DCIS, punctate microcalcification, and clusters containing <10 ecks of microcalcification were more common. Ductal carcinoma in situ showing more typical malignant features such as the rod shapes and a ductal distribution were more common at the time of diagnosis[15] (Figure 6). Therefore, early detection of high-grade DCIS requires recall and assessment of both mammographically suspicious and nonspeci c, indeterminate microcalcification clusters."
http://www.medscape.com/viewarticle/462246_4

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Here is what I'm wondering. I did extended breastfeeding, and child-led weaning. I still had milk present in my breasts (albeit not very much) when my son was 3 years old. My child is now 4, and I have no more milk. I cannot express any, and haven't been able to for a year.

I'm wondering if the extending nursing (having milk present in the mammary glands) for years could have caused all of these "abnormal microcalifications." I'm wondering if maybe having such calcium in the breasts may be "normal" for women who have nursed for a long time.

I have done extensive searches online, but haven't really found anything to truly validate my theory. I did read in a few places that sometimes some microcalifications may be from having milk in the mammary glands. However, I don't currently have milk. But I am wondering if it could be the vestiges from when I had so much milk - since I have SO MANY microcalcifications.

Please offer input. I am anxious, so good vibes are also welcome. I am having a second radiologist look at the mammogram results. As of now, the plan is to retest in April to see if any microcalcifications have grown or changed. If they have, then to go from there. On one hand, I'm relieved to wait until April. I always try to resolve things naturally first. On the other hand, given my family history (There were 4 of us kids. Both of my brothers are dead from cancer at young ages, and my sis is a living survivor of breast cancer), I want to stay on top of things. I have a host of other serious medical issues as well. I want to get/stay well to watch my beautiful little boy grow up.

Thanks for reading. Please be gentle with me.
post #2 of 3
Thread Starter 
I'm still researching my theory (that the "abnormal microcalcifications" bilaterally in my first mammogram are related to extended breastfeeding.)

I just found this, which does seem to support my thoughts.


"A 33-year-old woman with a strong family history of breast cancer who was referred for mammography 5 weeks after completing lactation was found to have new diffuse bilateral microcalcifications in the breast ducts. Contrast material–enhanced magnetic resonance imaging of the breast showed bilateral patchy areas of abnormal enhancement. Large-core needle biopsy showed diffuse calcifications within expanded benign ducts in a background of lactational change, without evidence of malignancy. To the authors’ knowledge, these calcifications have not been previously reported and are possibly related to milk stasis or apoptosis associated with lactation."
http://radiology.rsnajnls.org/cgi/co...full/217/1/247
http://radiology.rsnajnls.org/cgi/reprint/217/1/247.pdf


I also found a post (link below) from 2005 of a woman posting about the same issue that I currently have. Unfortunately, there were no responses to her post back then, so there is no more elaboration on this topic.
http://www.mothering.com/discussions...d.php?t=234870
post #3 of 3
Thread Starter 
And I also found these sources. I want to share this because this is a concept that I haven't heard mentioned much. (And according to these sources, it's not reported much. I'd like to see more women be aware, and not be frightened in the face of what might be "normal" even though conventional science doesn't consistently say that yet.)

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OBJECTIVE. We sought to describe the mammographic appearance of calcifications associated with histologically confirmed lactational changes of the breast.

CONCLUSION. Calcifications associated with lactational changes of the breast may have a suspicious appearance on mammography. These calcifications may be identified on a patient's original screening mammogram or may be a new finding on an annual screening examination. Correlating a clinical history of recent lactation or a postpartum state is important in establishing a concordance between the mammographic and histologic findings. However, despite the benign nature of these calcifications, biopsy is recommended because of their suspicious morphologic features.

We present four cases of postpartum patients in whom mammographically detected suspicious calcifications were histologically shown to represent the sequelae of lactational change alone.

http://www.ajronline.org/cgi/content/full/179/3/685

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"Abstract: A case of postlactational microcalcifications is reported. A 42-year-old woman presented for screening mammography 2 months after completion of breast-feeding. Comparison to her pregravid screening mammogram revealed the appearance of multiple groups of indeterminate microcalcifications bilaterally (BIRADS IV). She underwent bilateral stereotactic core biopsies of representative areas, yielding benign pathology. There have been anecdotal accounts and five reported cases of lactational microcalcifications in the radiology literature. We discuss the possible etiologies as well as implications of this mammographic finding."
http://www3.interscience.wiley.com/j...TRY=1&SRETRY=0

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I'm so exhausted. Must go to sleep now!
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