Can anyone help me re: 3rd m/c

[PinkLady73]

So I'm in the process of miscarrying my 3rd time in 9 months. I was 5w6d on Friday when I started bleeding :( I am going to the doctor tomorrow and this is a doctor whose nurse blew me off when I got my BFP and asked to have betas drawn and my progesterone checked. She said "we don't do that". I told her I had 2 previous m/c's and she still wouldn't hear me. I had met with a midwife last week because I wanted a homebirth but I feel like I'm ready to have some testing done now to see what my problem is. What should I ask for? What if he blows me off again? I really want a new doctor but it took forever to get this one because none of them take new patients if you are not PG! This is so frustrating because this is the only group that accepts my insurance. There is only one RE in my city and I have to have a referral I'm sure. I don't know exactly where to start. I am going to take a few cycles off from TTC right now so I can heal and hopefully get some answers, but I am scared I have no options and I just want my doctor to take me seriously and help me!

In the meantime is there anything else I can try such as herbs or alternative medicine? I would appreciate any suggestions. I'm willing to do just about anything to get to the bottom of this or just have a pregnancy that I can carry to term. I'm obviously fertile enough to get pg but at 35 who knows how long that will last? :(

[Quate]

Oh PinkLady, :hug. I don't understand why you couldn't get them to check your progesterone levels, but I think low progesterone or other hormonal imbalances can be a cause for repeat early miscarriages from what I've read.

[jmo]

I'm so sorry for your losses. I've had 3 m/c's in the last yr so I understand what you're going thru. I would definitely suggest getting some testing done if nothing else just for your peace of mind. Most drs will definitely run an "adverse pregnancy panel" after 2 or 3 losses. If this dr won't, I'd keep looking until you find one. Basically you want to be tested for immune issues and blood clotting disorders; these are two of the main casuses of recurrent pg loss. Also, it's a good idea to have your thyroid and prolactin levels checked. A referral to an RE would be ideal but an OB could run these tests for you too.
Do you chart your cycles? Any idea how long your lutuel phase is?

[PinkLady73]

Thank you for your replies! It helps to be able to come here for advice.

jmo Yes I do chart! I actually only started charting on May 1st when I desperately wanted to try to get pg again. The first 2 mc's I didn't know how far along I was but it was very early. So based on my 2 cycles charting (mine are rather long) I know that on my first cycle I had a 16 day LP and the 2nd cycle I got a BFP at 11 DPO, so I don't really know. I have heard that people can have a progesterone deficiency with a normal LP but I know that isn't the norm, right?

So I did see my OB today and he is going to start some testing which has me relieved. Basically we're starting off with another beta and progesterone and he is testing for my blood type and antibodies (I think?) because I told him when I went to the ER on Friday they tested me and I am RH negative. I did get the Rhogam shot there but I didn't know my blood type. He said that my cervix is still closed and it was on Friday's pelvic too so he said that could indicate that my m/c is not complete. He also said that my uterus is still measuring at 6 weeks and if my beta number is higher than 70.3 (the first one) then I could have a tubal pregnancy? I am praying that is not the case. So after these first tests come back we will know what to do and he is going to check me for clotting issues and chromosomal issues I guess. I did have my thyroid checked in March after having some hormonal issues and all that came back negative. I know she tested for all levels and not just TSH but I don't know if that is everything or thorough enough. I am willing to get another one if there is more comprehensive info that wasn't done the first time. I will ask too about the prolactin. If after all of that I don't have any definitive answers I will request a referral to an RE. I am feeling a lot less desperate because he is working with me and even though I'm still devastated I'm feeling slightly more hopeful that I will one day have a baby in my arms!

ETA: JMO did you get any answers after your losses?

[labortrials]

Why does he think this is a missed miscarriage? Is it possible that it was just too early to see the fetal pole? Some women with retroverted uteri will have babies that "hide" sometimes until 8 weeks! Did they see the yolk sac? Sorry, I don't want to give you false hope, but please do insist on a repeat ultrasound in a week if you haven't miscarried by then. :(

I too suffered 3 losses in about 9 months this past year. Devastating. :Hug
I too begged for the OB to test my progesterone; she refused - "we don't do that, and even if your numbers were off, we wouldn't treat anything." I have since transferred to a different practice. I do still really want to do a homebirth, but after all I've been through, I'm not probably going to go that route when I get pregnant again.

My bloodwork came back clean . . . except for a friggin' PROGESTERONE DEFICIENCY. So, this RE I've been seeing recommends that I do HCG shots in the luteal phase followed by progesterone shots when pregnant. Unfortunately, I do have a smallish fibroid that is distorting my uterine cavity, so I'm going to have a hysteroscopic myomectomy.

I hope you find your answers. Keep us posted, and feel free to join us at the hope and healing thread (if you haven't already).

~ Kimberly (ps, you can read my saga at my weblog if you're interested)

[PinkLady73]

OMG, Kimberly, I can't believe it's your progesterone. I am going to be so angry if I have a progesterone deficiency because I begged them to test it when I got my BFP and they wouldn't. I will never forgive them or myself for not pushing harder. On the flip side though at least I will have an answer and know how to treat it next time (hoping there is one). I just can't believe they said that they wouldn't treat it if it was. That is crazy!

So speaking of ignorant doctors, when I went in there yesterday I took my chart with me. He kept treating me as though I weren't in the middle of a m/c and he asked me if I knew my EDD. I told him 3/21 and he got out his stupid wheel and asked me when my LMP was. I told him June 6 and he said then your EDD is 3/14. I said YES if I had a 28 day cycle, but you can see right her ON MY CHART that I ovulated on CD23 and therefore my EDD is later than that. He said well, we still have to go by LMP. I was like, Look, you FOOL, that is not right! :irked: Anyway, I was stunned that they could be so stupid when I had the proof in his face. He didn't even look like he knew anything about my chart and probaby didn't.

Oh and to answer your ?? about the missed m/c, he just said that if my levels go up that it could indicate that I'm still pg and could be a tubal pregnancy so then I will have an u/s. I haven't had an u/s at all yet. But I just know I'm not pg anymore, because I have no symptoms whereas a week ago, I had a ton of symptoms. I just don't believe it's possible. :( So today I'm hoping to get the results but I"m not hopeful with these people. He says one thing and they say another as far as how long it takes the labs to come back. But I'll definitely keep you posted and I would love to join your other thread. Thanks!

[labortrials]

I'm so sorry you're going through this. The really need to do a u/s to see if you have (1) gestational sac, (2) yolk sace, (3) fetal pole (which may or may not be visible). It doesn't mean that you're NOT m/cing (:Hug), but it does help rule out an ectopic m/c. Just cuz your numbers may increase doesn't mean that you're having a tubal or molar pregnancy! Google "Misdiagnosed Miscarriage" or look on my weblog for a link to that site. There are AWESOME forums there for people who are trying to figure out WTF is going on when they're going through this.

And to answer your question, YES, she refused to test them and YES a pronounced LPD was discovered. And YES, I'm so so mad though it doesn't do any good b/c it's in the past. I will write her a letter and let her know that I did find a bona fide LPD. I doubt she'll learn anything though.

Current OB doesn't believe a true LPD is terribly common but is at least willing to treat for it.

Oh, and I have a short-ish luteal phase but not abnormally so. My progesterone dropped from 20 (good) to 3 (piss poor) in 48 hours. Pretty drastic, I must say.

[jmo]

ETA: JMO did you get any answers after your losses?

No, nothing at all. I've seen an RE and they have run every test imaginable and it all come back normal. We actually did a chromosomal analysis on the last baby and it was normal, though, so I have a hard time beleiving it's all bad luck. Who knows. It's incredibly frustrating. I just found out I'm pg again...for the fifth time now. Fingers crossed.

A 16 day lp is great, though. It is still possible to have low prog, I think. I'd ask for a prog test 7 days after you ovulate on your next cycle. That should give you an idea. Good luck.

[PinkLady73]

JMO Oh my gosh, CONGRATULATIONS!! I really hope it works out this time. I'm so happy for you and scared for you. I can only imagine how nervous you must be. This MUST be the one though!

Kimberly Well I got my results back and my beta is down to 8. The pissy thing is that I get a call back from the medical assistant and not a nurse or anyone who can tell me anything. FIrst of all, she just said it's 8. I said well what about the other tests. She had to look again. She didn't even read farther than that? So then she said my progesterone was .9 but didn't offer any explanation of WTF .9 means. Is that bad? Is it normal? Does it matter since it's not the right time to test my progesterone? I DON'T KNOW and she didn't say. Then she said my blood type is O- and that was it. I wanted to talk to someone about where to go from here. He said that after these results we'd do some other tests, but when? Am I supposed to make another appt myself? Am I supposed to ask for these things myself? I'm so frustrated and depressed because I just want my baby back. I want THAT baby back! :angry And I was very busy at work and didn't have time to get into anything further with her. I think I'm just going to hunt for another OB and explain my situation and see if they will start some testing or else just call the RE and see if they will see me. The only problem is my insurance not paying for that without a referral so I don't know what to do really. Oh, and she just said that since my beta was 8 that I have probably passed everything on my own and so that is that. I'm done and my 3rd baby is just gone and who knows why?

[Pinion67]

i am so sorry we just had our 9th m/c ( well 6th m/c one stillbirth ) and i so understand your pain. i aqm so very grateful for the 5 we have but i still miss the other 11 ( my sons twin ftt and the stillbirth was twin boys) i dreamed and hoped for . I wish you were closer to texas - the best ob yn / fertility sensitive doc - dr john maxey- would jump thru every hoop to help you . He did for us- all i can do is pray you find someone who listens to you and helps you , and that you stay hopeful, heal quickly and have as many babies as you want.
may God lovingly bless

[brightonwoman]

First of all, I know I don't ovulate on CD 14, so I always lie to the dr, and tell him that my LMP was whatever day happens to be 14 days before the day I know I O'd. Then he gets the right date. How's that for complicated!!!

I also want to make a comment about progesterone levels--they have only been testing levels for a couple of decades, so 'normal' is based on that research. However, there are those who theorize that human levels of progesterone used to be much higher, so even if you come in at 'normal' that doesn't necessarily mean that your levels are 'good' does that make sense? Ditto on thyroid hormones--my mother has had hypothyroid for about 7 years now and has been through everything with it, and she's found that the main thing we know about thyroid hormones is that we don't know very much...

On the topic of miscarriage though, I also had multiple miscarriages. Happy thought number one--I miscarried 6 times in two years but then I had a perfectly healthy baby and actually a totally uncomplicated and easy pregnancy. So there is hope!
If you have had a third miscarriage (are they documented? meaning do medical providers have records of all three?) then you are statistically a 'cronic aborter' I know it's a horrible HORRIBLE term, but that's what they call it. Anyway, you don't need a fertility specialist--obviously you have no issues with getting pregnant. Most doctors will say you should do a fertility workup but that's all wrong. Yes, some of the things you should do are the same as fertility (hormone testing etc), but some are different. For example, there's no need for your partner to have his sperm count checked. Seriously it blows my mind that some Dr's do that for miscarriage! I mean, DUH! What you actually need is a recurrent miscarriage workup, and those are hard to come by. There are not many doctors who specialize in that...I happened to be very lucky and lived less than an hour from one (he worked at the University of Utah research facility which has a massive medical center). If you're in CA, I suspect he is the one nearest you, although there might be someone closer. Honestly though, my reccommendation is to get online and look up the contact info for Dr Ware Branch at the U of U medical in the Recurrent Miscarriage office. Call them and explain your situation and ask if they can recommend anyone in your region. If there's somebody there, Dr Branch's office should know.
I can tell you what tests we did for me:
hormone levels (progesterone and I think another one)
thyroid
2 or 3 immunoglobin tests (there are some clotting issues which some researchers believe are linked to m/c)
and there may have been something else...I think they took 6 tubes of blood, but I don't remember exactly what they were all for. I do know that the tests came back without any answers--Dr Branch said that 90% of the time testing does not give any answers, however they do collect the data and are hoping over time to learn something from it all.
The last thing I had was an HSG, hystero-salpingogram. In other words they shot a dye into my uterus and did an x-ray of it and it showed the shape of my uterus, so they could see if I had any issues with being weirdly shaped, having a septum, or anything like that.

Anyway, I don't know if that's helpful, but honestly, I would call Dr Branch's office. I don't have the number anymore, but it's a University, it shouldn't be too hard to chase down.

[brightonwoman]

Oh, I meant to add--after the third miscarriage, when you have the statistical position of being a recurrent miscarrier, you should be able to get insurance to cover testing. So as much as it sucks to keep losing babies (:hug I know), there is one teeny weeny silver lining to it.

[brightonwoman]

Oh, I meant to add--after the third miscarriage, when you have the statistical position of being a recurrent miscarrier, you should be able to get insurance to cover testing. So as much as it sucks to keep losing babies (:Hug I know), there is one teeny weeny silver lining to it.

[labortrials]

Good points, BRIGHTON.

If you are in CA, then perhaps you could go to RIA in LA. http://www.rialab.com/miscarriages_prevented.php has some great information.

Hey, if you want a referral to a RE, just TELL your OB that's what YOU want to do. After 3 miscarriages it's perfectly normal and appropriate to want to see a specialist.

I don't know what to tell you about a .9 beta. I do know that if your HCG is below a certain number that you're considered unpregnant.

The way we determined that my old eggs don't suck and that my progesterone DOES suck was: CD3 blood draw (estradiol & FSH), CD21 - actually 7 days after ovulation, they insisted I do OPKs to determine my ovulation date (progesterone) and CD24 (progesterone).

My OB did a HSG to see if possibly the cesarean in 2004 had damaged my uterine structure. What he thought he found was evidence of a Mullerian Duct Anomaly - possibly uterus didelphys. The RE looked at my x-ray and said that I don't have a structural anomaly. He did 2D u/s and determined that my fibroid (which I had when I was pregnant with DD and it's still the same size) is distorting my uterine cavity. He wanted me to do a laparascopic myomectomy - think he jumped to that b/c I've already had a c/s so in his mind my uterus is already compromised (once a c/s always a c/s). I didn't schedule the surgery. He later recommended a saline u/s which convinced me that at least a hysteroscopic myomectomy might be appropriate. He's "hopeful" that he can remove the fibroid that way. I have not authorized him to do the lap myomectomy if the hyst myomectomy is unsuccessful.

I'm still trying to reach my OB's nurse to give her the new info - hyst myo and shitty progesterone. When I told them that the RE was recommending the lap myo, they thought that was pretty crazy, and in fact, the nurse was like "Wasn't one scar in your uterus enough?" EXACTLY HOW I FEEL.

So, in other words, it took some resistance on my part and a couple of extra appointments with this RE for him to finally wake up and listen to me that the integrity of my uterus actually matters. Plus the more scar tissue introduced to the uterus, the worse it can be for your fertility, and it just sounded like the lap myo would have bought me at least 2 more uterine scars (one for the myo, one for the repeat c/s that would have been necessary for any births following the procedure).

Alright, sorry to be so long winded. It's just that you never know who might search here for info on myomectomy, RPL, hormone imbalance (YES IT DOES HAPPEN and YES IT DOES MATTER), etc.

I'm so sorry you've lost another baby. I believe my baby will come back to me. I think our son was trying to get to me these last 3 times. What's strange is that I don't think he will be our next baby. I think he'll be our 3rd living child. Strange, eh?

:Hug

[leomother]

Hi Pinklady73,

I am 20 weeks pregnant this week and am at home for a week (putting myself on modified bedrest) and frequenting all the pregnancy websites for clues etc. I have an incompetent cervix and have suffered to 2nd trimester losses at 21 weeks in 2007. I since received a cerclage at 12 weeks. I just saw this cream yesterday that may help, not sure but since I had pre-term labour before (due to incompt cervix), I thought I would give it a try.
Refer:
http://www.happypmscream.com/recommend_progesterone_cream.htm

and Good luck!

[heatherh]

I agree with labortrials - you have every right to insist on a referral to a specialist. If the OB won't refer you (which would be completely ridiculous), can your primary care physician refer you instead? Maybe they're easier to work with?

[railyuh]

Definitely ask for a referral to an RE, and like another poster said, if your OB balks then ask your primary care physician--that's what I did. After my 3rd m/c my OB said that it was just bad luck, I insisted that he run a thrombosis (blood clotting) panel and he said it wasn't necessary but would do it for my piece of mind. What do you know, something came up on my panel. He gave me his "protocol" treatment after admitting he didn't know much about my condition. I didn't even bother asking him for a referral. I went to my primary doc and they gave me one without a problem.

:hug: mama, it sucks to go through this and I hope you find a doctor who takes your concerns seriously. You shouldn't have to go through more losses before someone tries to figure out what is going on.

[PinkLady73]

railyuh I'm definitely requesting a referral to an RE! Especially since my OB didn't know anything about charting. I lost faith in him then. He did say that he was going to test me for clotting disorders though, so hopefully I will have that done soon and I hope I can get an appt with the RE within a reasonable time frame (that being a reasonable time frame for ME of course):wink


heather thanks for that suggestion. I hadn't thought of it, but if my OB won't refer me then I will definitely ask my PCP!

leomother hanks for that link, but I did use progesterone cream during the entire pregnancy. And actually I did stay pg longer than any of my other 2 prgncy's, so maybe it helped a little but I need more? My doctor said that if I do have a prog deficiency that prog cream will not be enough. But I also read this evening that if you take a prog supplement you have to take it from the time of ovulation or it isn't *as likely* to work. I didn't start using the cream until 7 DPO, so I doubt that really mattered but who knows? I'm hoping he'll just put me on prog from ovulation next time and it can't hurt anyway, right? And congratulations on your baby! I hope everything is okay with you.

labortrials I hope that all the info you gave on the myo is helpful to someone. I am sure you're not the only one going through that.I'm so sorry, it sounds just awful. My hcg was actually 8 but yeah, anything under 5 I think means you're not pg. So it was close. I'm pretty sure the m/c is done and over with at this point. I'm lucky that it wasn't a tubal, and I am just going to look at that silver lining right now! I dread having to do an HSG, and I know it's not horrible because I've assisted with them many times(I'm an xray tech) but i don't want one myself!! But I'm willing to do whatever it takes.

brightonwoman Why didn't I think of that? Next time (FX'd) I am so going to lie about my LMP to get the EDD that is CORRECT! I have to laugh at how sad it is that we have to lie because we know what is correct and the doctor's don't! That is just really sad! Thank you thank you for posting the tests you had. I am copying those and I know he's doing clotting tests and progesterone (again when it's time) and if those don't show anything hopefully I will have an RE appt by then!

pinion67 OMG, I feel just awful for you! I cannot even imaging going through what you have. So where in TX is that doctor? I am from Arkansas so I grew very close to Tx and have a ton of family there in Dallas and HOuston. And thank you for your kind words! It is so nice to have you guys to talk to and help me get answers. I really appreciate it!

So I had a better day today. I was in a bad place yesterday, but I guess it will just be like that now and then. I'm ready to TTC again but I won't until I get some answers. I don't want to risk another one just for the sake of getting pregnant again right away. Hopefully in the next 2 cycles I will feel confident about trying again.

[labortrials]

Mostly with the charting biz, some OBs don't count that as reliable information. I told the RE, for instance, that I knew I ovulated on x day. He said how do you know? Did you do an OPK? I said, no I can tell by my CM, the fact that my os is open, and the fact that I have ovulation pain on one side. He told me that wasn't very reliable.

So before the progesterone testing, I had to go buy a friggin' useless pack of OPKs to tell me what I already know - when I ovulate. :irked: Anyway, don't leave your OB just because s/he doesn't know about charting. Most could give a hoot about your chart.

My HSG wasn't horrible because my regular OB injected the dye himself. It was labor-like cramping for a moment, and then nothing too terrible. Some residual cramping and stuff for a couple of days. The SHG was even easier thankfully.

[PinkLady73]

Why is it that they will trust the OPK but not your temp shift and CM patterns? I don't get that at all.

Well I have an appt with my OB on the 7th so I am excited actually about starting to have some tests done. I will update and in the meantime I am going to try to stay positive! Thanks for all the support i have gotten here. It is such a blessing to have a place to go for help and support after something so traumatic!

[brightonwoman]

They trust the OPK because it's 'scientific' and your CM observations aren't. LAme, but true. If you had a degree in reproduction, they would probably still not trust your charting unless you did it on an expensive computer program and provided lab samples :bang

concerning progesterone, some people feel that using the vaginally inserted capsules is more effective than the cream...it's something to consider. Most doctors are willing to prescribe them even if they're not convinced that you need them, because it's sortof a "can't hurt might help" scenario. Also, i have gotten my progesterone cream from www.puritain.com they have been MUCH more affordable than my local herb shop.

fingers crossed for you!

[PinkLady73]

I heard that about the vaginal suppositories so I am going to request that if he is willing to give it to me. My game plan is to "try" to avoid for this first cycle but if I accidentally BD during my fertile phase I will ask for the Rx to start taking it as soon as I O. If I don't BD during ovulation then I want the progesterone blood work at 7 DPO and try and see if it is even an issue. I am charting but I'm not sure if this cycle is going to be long and weird or not. So I'm just taking it one day at a time I guess. However, my first cycle after my 1st m/c came back normally. I have longer cycles anyway like 35-40 days so far. I'm considering acupuncture as well. But I'm not sure if I can afford it. I want to call around and see if there are any acupuncturist's here that specialize in fertility.

[PinkLady73]

I just wanted to update and if anyone has any input on the tests that I'm getting (or not getting) please feel free to offer any advice!

I went to my OB yesterday and I am happy to say that he is being very proactive and he has ordered these tests:

APA panel
Factor V Leiden mutation
prothrombin gene mutation
protein c antigen
protein s antigen and activity
homocysteine level
antithrombene III mutation
complete blood count
basic metabolic panel
chromosomal testing for me AND J
pelvic ultrasound


And he is getting the referral from my insurance company and I'm going to see an RE now! After the test results come back I am going to make an appt. and see if there is anything else he wants me to do. I'm so happy to feel like something is getting done. And it feels weird to say this, but I hope they find something. I mean who wants to have something be wrong with them, but at the same time I will feel like there is a reason for these losses and not just "bad luck". And at least that way, there is a solution hopefully! I'm definitely not going to TTC this cycle then until the results are back and I see the RE. And I'm going to start acupuncture too. I'm hoping that all of these things will lead me to a sticky baby!! :)

[momoftworedheads]

I am so sorry that you have had to go through all of this! It sounds like you are getting a lot of good testing. Are they doing MTHFR as well as homocysteine level?

Also, I have had 4 losses in 2 years, but 3 being in the last 10 months. It took me going to an RE, having an u/s, HSG and doing testing for the OB and MW to see that I have a Progesterone deficiency. I take Prometrium orally from day 16 to when my period comes. This month I am asking for the suppository instead.

Lots of light and love to you!

Best wishes and keep us posted.

Take care,
Jen

[PinkLady73]

Jen, Thank you and I'm sorry for your losses as well. It is really hard to deal with. I hope that you get a sticky baby soon and the progesterone works for you. And thanks for posting, I need to update. I just didn't know if anyone was still reading this. So why did they do an hsg if you are getting pregnant? I was wondering if he would order that for me and I wasn't sure why I would need one, but we'll see I guess.

So I got the blood drawn (13 vials :eek) and I waited forever it seemed like to get the results. It was actually a week. They were all PERFECT. Seems like I am very healthy overall. However, they said that the MTHFR and the prothrombin Factor II were still pending. So I waited a few more days and then they told me that I had to come back for a redraw for those two! :irked: So I did that today, and I have to wait again for the results of those. She promised me by Tuesday or Wednesday I should know. I better. I am very irritated lately with all these people. I do have an appt. with the RE on Sept 9th, so I am hoping to get these results and if they are negative then I'm back at square one I guess. So that is where things stand so far. Oh and my homocysteine level was 4.8 so it was low. I have been doing tons of research on the MTHFR and it scares the crap out of me and I'm hoping that I don't have it and that my issue is something like progesterone. Of course I am hoping that it's not anything bad but I would actually be satisfied with just an ANSWER I suppose.

Oh, and also to update, I finished my first cycle since the m/c and I am on CD 2 and ready to start again! So maybe I will join the other thread now. I just wanted to wait this cycle out and I am happy that I ovulated on time. The only weird thing is that my LP was 3 days shorter. Not sure if that means anything or not, but it was still 13 days which is okay I guess.

[PinkLady73]

Well, just in case anyone reads this, I got the labs back and I am homozygous for the MTHFR C677T mutation and negative for the A1298C mutation. So I am freaking out, because of all the contradicting information that I get on this. I don't want to risk another m/c and I don't even know if this is the problem or not. :( I guess I will see what the RE says about it next Tuesday.

[Quate]

:hug I don't know what that means at all but I hope that you will be able to find some good answers.

[WeasleyMum]

Pinklady :Hug I don't really know anything about that paticular thing, but I know the feeling of waiting for results and hoping/fearing that they'll find what's wrong. For me, every test came back OK but the progesterone, but then I lost the 4th pregnancy even WITH progesterone. WTF.

At least you seem to be in the hands of a competent practice now, for whatever it's worth.

[mischievium]

Pinklady :Hug I hope you get more answers from your doctors soon about what this means for you and TTC. A thought-- if you are looking for more people who may have dealt with/ are dealing with MTHFR, maybe try posting in the infertility forum or even possibly the pregnancy forum? I know I have seen other posts about MTHFR, but I can't remember where exactly.